The overlap of storage, voiding and postmicturition symptoms and implications for treatment seeking in the USA, UK and Sweden: EpiLUTS

Abstract

seeking as the dependent variable and the bother of individual symptoms as predictors. RESULTSThe survey response rate was 59%. The sample included 30 000 participants (14 139 men and 15 861 women); 71% of men and 75% of women reported at least one LUTS, and about half reported LUTS from more than one symptom group. Rates of bother were greatest for those who reported multiple storage, voiding and postmicturition LUTS (men 83%, women 89%). Less than a third of participants with LUTS from all three groups reported seeking treatment. Consistent correlates of treatment seeking across genders included bother due to weak stream, incomplete emptying, perceived daytime frequency, nocturia and urgency. There were also significant associations for several types of incontinence, most commonly stress incontinence in women and leaking during sexual activity in men. Despite high rates of symptom overlap and symptom-specific bother, few participants sought treatment for LUTS. CONCLUSIONCommon conditions such as BPH and OAB are treatable, and clinicians should proactively ask patients about urinary symptoms. Given the many types of LUTS that patients experience, it is imperative that clinicians assess all LUTS to ensure that appropriate treatments are prescribed.

Drug treatment patterns for the management of men with lower urinary tract symptoms associated with benign prostatic hyperplasia who have both storage and voiding symptoms: a study using the health improvement network UK primary care data

“…Similar results have been described in the EpiLUTS survey, which reported that only 11.2-17.6% of men with LUTS and both storage and voiding symptoms were prescribed medication 18 . Initial treatment with a 1 -blocker monotherapy may not adequately control symptoms in men with storage symptoms based on data which reported only 35% of men had improved symptoms with a 1 -blocker monotherapy, whilst a 1 -blocker plus antimuscarinic combination therapy improved symptoms in 73% of those men who did not initially respond to a 1 -blocker monotherapy 19 .…”

Hypovitaminosis D is associated with lower urinary tract symptoms and benign prostate hyperplasia in type 2 diabetes

“…Lower urinary tract symptoms (LUTS) in men are categorized into storage symptoms (increased daytime urinary frequency, nocturia, urgency, and incontinence), voiding symptoms (slow stream, splitting or spraying, intermittent stream, hesitancy, straining, and terminal dribble), and post-micturition symptoms (feeling of incomplete emptying and post-micturition dribble) (Abrams et al, 2002;Sexton et al, 2009). The International Prostate Symptom Score (IPSS) questionnaire investigates the presence of these symptoms in seven questions, allowing to establish the severity/quantification of LUTS (Barry, 2001).…”

Relationship Between Anxiety and Lower Urinary Tract Symptoms

“…This finding revealed that LUTS severity is associated anxiety and QoL consisted with previous study. LUTS which contains obstructive (voiding) symptoms and irritative (storage) symptoms can be quantitatively assessed by questionnaires like the IPSS [2][3][4]. In Tanik's study, Qmax and IPSS were correlated with prostate volume, which is related with the clinical status of patients [15].…”

“…Lower urinary tract symptoms (LUTS) secondary to BPH are prevalent and interfere with the quality of life (QoL) of older men [2][3][4]. The prevalence of BPH is about 40% for men in their fifties and reaches to 90% for men in their nineties [5].…”