The outcomes of reconstruction using frozen autograft combined with iodine-coated implants for malignant bone tumors: compared with non-coated implants

Shirai, Toshiharu; Tsuchiya, Hiroyuki; Terauchi, Ryu; Tsuchida, Shinji; Mizoshiri, Naoki; Igarashi, Kentaro; Miwa, Shinji; Takeuchi, Akihiko; Kimura, Hiroaki; Hayashi, Katsuhiro; Yamamoto, Norio; Kubo, Toshikazu

doi:10.1093/jjco/hyw065

Cited by 11 publications

(10 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, it is not easy to conquer the infection in recycled bone surgery as well as the other biological methods and endoprosthesic surgery. We consider that rigid fixation, less surgical time, or use of recent antibacterial-agents-coated implants [27,28] are desirable in musculoskeletal tumour surgery.…”

Section: Discussionmentioning

confidence: 99%

Knee joint preservation surgery in osteosarcoma using tumour-bearing bone treated with liquid nitrogen

Higuchi

Yamamoto

Nishida

et al. 2017

International Orthopaedics (SICOT)

Self Cite

View full text Add to dashboard Cite

Purpose To preserve the joint structure in order to maintain good limb function in patients with osteosarcoma, we perform epiphyseal or metaphyseal osteotomy and reconstruction using frozen autografts that contain a tumour treated with liquid nitrogen. There are two methods of using liquid nitrogen-treated autografts: the free-freezing method and the pedicle-freezing method. The purpose of this study was to evaluate the results of intentional joint-preserving reconstruction using the free-freezing method and the pedicle-freezing method in patients with osteosarcoma.

show abstract

Section: Discussionmentioning

confidence: 99%

Knee joint preservation surgery in osteosarcoma using tumour-bearing bone treated with liquid nitrogen

Higuchi

Yamamoto

Nishida

et al. 2017

International Orthopaedics (SICOT)

Self Cite

View full text Add to dashboard Cite

show abstract

“…The occurrence of pin tract infection following external fixation in patients with malignant tumors makes controlling infections difficult during postoperative chemotherapy [ 17 , 18 ]. Iodine-coated implants were found to inhibit biofilm formation on the implants and significantly reduce implant-associated infections [ 19 – 21 ]. The preparation of the iodine-coated implant was carried out in the same way as the method we reported earlier [ 20 ].…”

Section: Discussionmentioning

confidence: 99%

Limb saving surgery for Ewing’s sarcoma of the distal tibia: a case report

et al. 2018

Self Cite

View full text Add to dashboard Cite

BackgroundEwing’s sarcoma is a primary malignant tumor of bone occurring mostly in childhood. Few effective reconstruction techniques are available after wide resection of Ewing’s sarcoma at the distal end of the tibia. Reconstruction after wide resection is especially difficult in children, as it is necessary to consider the growth and activity of the lower limbs.Case presentationA 12-year-old Japanese boy had presented with right lower leg pain at age 8 years. Imaging examination showed a bone tumor accompanied by a large extra-skeletal mass in the distal part of his tibia. The tumor was histologically diagnosed as Ewing’s sarcoma. The patient received chemotherapy, followed by wide resection. Reconstruction consisted of a bone transport method involving external fixation of Taylor Spatial Frame. To prevent infection after surgery, the external fixation pin was coated with iodine. One year after surgery, the patient showed poor consolidation of bone, so iliac bone transplantation was performed on the extended bones and docking site of the distal tibia. After 20 months, tibia formation was good. Three years after surgery, there was no evidence of tumor recurrence or metastases; bone fusion was good, and he was able to run.ConclusionsThe bone transport method is an effective surgical method of reconstruction after wide resection of a bone tumor at the distal end of the tibia, if a pin can be inserted into the distal bone fragment. Coating external fixation pins with iodine may prevent postoperative infection.

show abstract

“…Furthermore, the functional outcomes were excellent in two, good in one, and fair in two patients [59] . Although the infection rates facilitated by this technique were reportedly higher in pelvic compared to extremity tumors [59] , [69] , the introduction of an iodine plate or a prosthesis reduced these rates after the use of frozen autografts in a cohort of 62 patients, including patients with pelvic tumors [71] .…”

Section: Autograftmentioning

confidence: 97%

Periacetabular reconstruction following limb-salvage surgery for pelvic sarcomas

Fujiwara

Christ

Bartelstein

et al. 2021

Journal of Bone Oncology

View full text Add to dashboard Cite

Highlights There is no standard procedure for periacetabular reconstruction following pelvic resections. High complication rates are associated with the use of massive implants/grafts. Deep infection is generally the most common cause for reconstruction failure. Functional outcomes decline with the occurrence of severe complications. Further efforts to avoid complications are crucial for improving outcomes.

show abstract

The outcomes of reconstruction using frozen autograft combined with iodine-coated implants for malignant bone tumors: compared with non-coated implants

Abstract: Reconstruction using frozen autograft combined with iodine-coated implants for patients with malignant bone tumor is very useful method in which good limb function can be gained with minimized risk of infection.

Cited by 11 publications

References 22 publications

Knee joint preservation surgery in osteosarcoma using tumour-bearing bone treated with liquid nitrogen

Knee joint preservation surgery in osteosarcoma using tumour-bearing bone treated with liquid nitrogen

Limb saving surgery for Ewing’s sarcoma of the distal tibia: a case report

Periacetabular reconstruction following limb-salvage surgery for pelvic sarcomas

Contact Info

Product

Resources

About