The Outcome of Prenatally Diagnosed Isolated Fetal Ventricular Septal Defect

Characteristics of Isolated Ventricular Septal Defects Less Likely to Close In Utero

“…This observational study probably was one of a few studies that followed fetuses with a VSD from the time of diagnosis at mid pregnancy until 1 month of age without therapeutic abortions in populations at low and high risk for congenital cardiac defects. In our study, 84% of prenatally diagnosed VSDs closed spontaneously in utero compared to 5.2% to 84% in previous studies . In our study, VSDs were diagnosed at an earlier GA (mean, 20.8 weeks; median, 19.1 weeks) compared to studies by Gómez et al (median, 30.4 weeks) and Paladini et al (mean, 24.8 weeks).…”

“…Consequently, we could observe the natural development of VSDs without a selective bias. Other studies only observed isolated VSDs; however, we followed both isolated VSDs and those associated with other cardiac defects.…”

“…The prenatal course of a VSD has not been adequately studied, especially in the low‐risk obstetric population. The prenatal resolution frequency of VSDs has been reported with a wide range of variations (5.3%–84%) in previous studies . The objective of this study was to determine the characteristics of VSDs that are associated with spontaneous closure in utero.…”

Defecto ventricular septal aislado. Reporte de un caso

“…Aunque no hay una definición universalmente aceptada respecto al tamaño del DVS, los estudios clínicos usan comúnmente la siguiente clasificación: pequeño < 4 mm, mediano 4 a 6 mm, y grande > 6 mm. Los DVS medianos y grandes pueden ser detectados intraútero tan pronto como a las 16 a 18 semanas de gestación; los pequeños a moderados pueden pasar desapercibidos durante la ecocardiografía fetal (7) . En nuestra paciente, el DVS correspondía a un DVS muscular medio y de tamaño pequeño, evidenciado en la ecografía de las 20 semanas y con la función Doppler.…”

Spatio‐temporal image correlation rendering mode visualizes the specific location and surrounding structure of ventricular septal defect

“…Based on the location of the VSD on the right ventricular surface of the interventricular septum, VSDs can be classified by several phenotypic variants, such as central perimembranous, inlet, outlet, and trabecular muscular defects (Lopez et al, ). Currently, the location and size of the defects have been implicated in the outcome of neonates with VSD (Huang et al, ). Thus, accurate distinction of these phenotypic variants is critical for correct diagnosis and therapeutic intervention.…”