The outcome of anorexia nervosa: a reappraisal

Hsu, Li-Yi

doi:10.1017/s0033291700009739

Cited by 94 publications

(54 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our initial evidence indicated this might be so, yet we were unable to confirm this in the full cohort; that is, bulimia (whether associated with anorexia nervosa or not) was not found to be more common among relatives of anorexic probands with concomitant binge eating than among relatives of pure restrictor probands. But again some caution is in order since the follow-up course of currently asymptomatic sisters is not yet known and the possibility that at least some of the bulimic sisters of probands will eventually progress to anorexia nervosa can not be discounted (Hsu, 1988). For these reasons we do not feel that the present findings make clear whether or not anorexia nervosa breeds true in families or confers increased risk for bulimia nervosa as well.…”

Section: Discussionmentioning

confidence: 56%

“…Other family studies have yielded convergent evidence of markedly elevated rates of major affective disorders in relatives of anorexics as compared to relatives of normal controls, leading some writers to advocate that affective conditions and anorexia nervosa may share a single common familial diathesis (Hudson & Pope, 1988;Strober & Katz, 1987, 1988. Whether or not this familial aggregation of affective disorders is explained by the presence of coexisting depression in a subset of anorexic probands remains uncertain.…”

mentioning

confidence: 99%

See 1 more Smart Citation

A controlled family study of anorexia nervosa: Evidence of familial aggregation and lack of shared transmission with affective disorders

Lampert

Morrell²,

Burroughs

et al. 1990

Int. J. Eat. Disord.

155

View full text Add to dashboard Cite

Lifetime prevalence rates of eating disorders and affective disorder were determined in biological relatives of probands with anorexia nervosa, affective disorder, and other types of psychiatric disturbance. Anorexia nervosa was found to cluster in families with intergenerational transmission, and was absent among relatives of controls. Significantly higher rates of affective disorder were found among relatives of anorexics with coexisting depression, suggesting that these probands transmit two disorders to relatives. The results indicate there is familial resemblance for anorexia nervosa, and that the liability is different from that operating in the transmission of affective disorders.

show abstract

Section: Discussionmentioning

confidence: 56%

mentioning

confidence: 99%

A controlled family study of anorexia nervosa: Evidence of familial aggregation and lack of shared transmission with affective disorders

Lampert

Morrell²,

Burroughs

et al. 1990

Int. J. Eat. Disord.

155

View full text Add to dashboard Cite

show abstract

“…Research on schizophrenic patients has found evidence linking PBCs and ventricular enlargement to premorbid abnormalities of personality and intellectual function, and to lifelong disorder (Cannon, Mednick, & Parnas, 1989;Weinberger, 1987). Hsu (1988) has noted that these premorbid personality, social, and familial problems, associated with chronicity in schizophrenic patients, are also associated with chronicity in anorexia nervosa. The correlates of chronicity in anorexia nervosa may also be linked to cerebral PBCs and associated cerebral damage.…”

Section: Chronicity Of Anorexia Nervosa: Neurological Abnormalities Amentioning

confidence: 99%

Chronicity in anorexia nervosa: Pregnancy and birth complications as risk factors

Bakan

Birmingham

Goldner

1991

Int. J. Eat. Disord.

View full text Add to dashboard Cite

The chronic form of anorexia nervosa (AN) affects about one‐quarter of patients and has serious somatic and psychological consequences. This paper presents evidence in support of the hypothesis that pregnancy and birth complications (PBCs) associated with neuropathology may be risk factors for chronic anorexia nervosa. There is increasing evidence that PBCs are risk factors for other psychiatric and somatic disorders. Recent findings of possible premorbid neuropathology in patients with anorexia nervosa suggest that PBCs may be risk factors for chronicity in anorexia nervosa. Topics discussed include the origins of constitutional vulnerability to anorexia nervosa, correlates of PBCs and of chronic anorexia nervosa, the relationship of PBCs to neurological and neurochemical abnormalities, chronicity of anorexia nervosa in relation to PBCs and to neurological and neurochemical abnormalities, and the research implications of the hypothesis that PBCs and associated neuropathology are risk factors for chronicity in anorexia nervosa.

show abstract

“…Long-term follow-up studies indicate that nearly 50% of the patients eventually make a full recovery, 20–30% show residual symptoms, 10–20% remain severely ill, and 5–10% die of related causes [3]. In order to explain this heterogeneity, different outcome studies that considered various possible prognostic factors have been conducted so far [4,5,6,7,8,9,10]. In particular, age at onset, age at index treatment, history of an eating disorder (ED), duration of the disease and BMI at onset have been considered, often with conflicting results [3,8,9,11,12,13,14,15,16].…”

Section: Introductionmentioning

confidence: 99%

Cognitive-Behavioral Therapy for Threshold and Subthreshold Anorexia Nervosa: A Three-Year Follow-Up Study

Ricca¹,

Castellini²,

Sauro³

et al. 2010

Psychother Psychosom

View full text Add to dashboard Cite

Background: Few long-term follow-up studies have evaluated the response to psychotherapeutical interventions in anorexia nervosa (AN). The effectiveness of individual cognitive-behavioral therapy (CBT) and the possible predictors of outcome in outpatients suffering from threshold and subthreshold AN (s-AN) were evaluated. Methods: At the beginning (T0) and at the end of treatment (T1), and 3 years after the end of treatment (T2), 53 subjects with AN and 50 with s-AN (all DSM-IV criteria except amenorrhea or underweight) were assessed by a face-to-face clinical interview and by self-reported questionnaires for eating attitudes and behavior (Eating Disorder Examination Questionnaire), body uneasiness (Body Uneasiness Test) and general psychopathology (Symptom Checklist, Beck Depression Inventory, State-Trait Anxiety Inventory). Results: No deaths occurred during the treatment and the follow-up period. At the end of the follow-up 34 subjects (33%) initially enrolled in the study obtained a full recovery. AN and s-AN patients did not show significant differences on most of the clinical measures at baseline and in terms of treatment response (T1, T2). The reduction in weight and shape concerns was associated with weight gain at T1 and T2, and the shape concern level at baseline represented the main risk factor for recovery and treatment resistance. According to survival analysis, patients with high shape concern had a lower probability of remission across time. Conclusions: The distinction between threshold and subthreshold AN does not seem to be of clinical relevance in terms of response to CBT. Shape concern rather than demographic or general psychopathological features represents the best predictor of outcome for CBT.

show abstract

The outcome of anorexia nervosa: a reappraisal

Cited by 94 publications

References 21 publications

A controlled family study of anorexia nervosa: Evidence of familial aggregation and lack of shared transmission with affective disorders

A controlled family study of anorexia nervosa: Evidence of familial aggregation and lack of shared transmission with affective disorders

Chronicity in anorexia nervosa: Pregnancy and birth complications as risk factors

Cognitive-Behavioral Therapy for Threshold and Subthreshold Anorexia Nervosa: A Three-Year Follow-Up Study

Contact Info

Product

Resources

About