The outcome of acute pancreatitis patients with acute kidney injury- Single centre study from North India

Mathur, Piyush

doi:10.15406/ghoa.2022.13.00522

Cited by 1 publication

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References 20 publications

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“…These results agree with (Amy et al, 2014 andMayumi et al, 2002). The severity of AP was associated with higher incidence of Acute Kidney Injury and increasing serum creatinine (Piyush.,2022). Serum pro-inflammatory results TNF-α and IL-6 had significantly changed at 6, 24, 96hrs.…”

Section: Discussionmentioning

confidence: 99%

Biochemical and histopathological changes of L-Arginine experimentally induced acute pancreatitis in male albino rats.

Disoukey,

Fararh,

Farid

et al. 2023

Benha Veterinary Medical Journal

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The biochemical and histopathological changes of L-arginine experimentally induced acute pancreatitis (AP) in male rats were studied. Forty rats were separated into two groups (20 rats each). control: rats were fed normal diet. Acute pancreatitis group (AP): AP was induced by injecting 300 mg/kg bwt of L -Arginine (Arg) intraperitoneally. Blood samples were collected after 6, 24 and 96 hours and 7 days. The separated serum samples were directly used for the estimation of amylase, lipase, ALT and AST activities besides glucose levels. Also, TNF-α, IL-6, NO, total cholesterol, triglyceride, urea and creatinine levels were determined. The results revealed substantial increases in serum amylase, lipase, ALT and AST values as well as TNF-α, IL-6. NO, serum urea and creatinine levels. Meanwhile, non-significant changes in plasma, glucose and serum triglycerides levels were observed, while cholesterol showed non-significant decreased specially at 6 and 24hrs and significant elevation at 96hr. post-induction of AP. Histopathological changes of Larginine treated group showed, focal degeneration and necrosis of the pancreatic acini at 24 hours post-induction of AP, while at 7 th day focal area of acinar epithelium regenerations was recorded.

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Section: Discussionmentioning

confidence: 99%

Biochemical and histopathological changes of L-Arginine experimentally induced acute pancreatitis in male albino rats.

Disoukey,

Fararh,

Farid

et al. 2023

Benha Veterinary Medical Journal

View full text Add to dashboard Cite

show abstract

The outcome of acute pancreatitis patients with acute kidney injury- Single centre study from North India

Abstract: The aim of our study is to access the risk factors for the development of AKI in patients of AP, and the disease spectrum and outcome of such patients.

Cited by 1 publication

References 20 publications

Biochemical and histopathological changes of L-Arginine experimentally induced acute pancreatitis in male albino rats.

Biochemical and histopathological changes of L-Arginine experimentally induced acute pancreatitis in male albino rats.

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