1977
DOI: 10.3171/jns.1977.47.4.0491
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The outcome from severe head injury with early diagnosis and intensive management

Abstract: In the belief that secondary cerebral compression, hypoxia, and ischemia materially influence the outcome from severe head injury, a standardized protocol was followed in 160 patients, with emphasis on early diagnosis and evacuation of intracranial mass lesions by craniotomy, artificial ventilation, control of increased intracranial pressure, and aggressive medical therapy. Of these patients, 36% made a good recovery, 24% were moderately disabled, 8% were severely disabled, 2% were vegetative, and 30% died. Th… Show more

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Cited by 825 publications
(224 citation statements)
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“…The factor of greatest influence on outcome is the time from injury to surgery. Patients that undergo DC within the first 4 hours following trauma have better outcomes compared to those who undergo DC after 4 hours (2,13,25,26,30). Münch et al reported a mortality rate of 30% for patients that underwent DC within 4 hours, compared to 90% for those after 4 hours (25).…”
Section: Discussionmentioning
confidence: 99%
“…The factor of greatest influence on outcome is the time from injury to surgery. Patients that undergo DC within the first 4 hours following trauma have better outcomes compared to those who undergo DC after 4 hours (2,13,25,26,30). Münch et al reported a mortality rate of 30% for patients that underwent DC within 4 hours, compared to 90% for those after 4 hours (25).…”
Section: Discussionmentioning
confidence: 99%
“…4,35 This expansion began with Lawrence Marshall's 2-part paper, with Part 1 focusing on the significance of ICP monitoring via a ventricular catheter. 32 Thomas Saul and Thomas Ducker followed in 1982 with an analysis of mortality rate stratified by ICP.…”
Section: Traumatic Brain Injurymentioning
confidence: 99%
“…Recent evidence suggests that mortality can be reduced without significantly increasing the number of people surviving in a vegetative or severely disabled stale. 1 In a review of avoidable factors in the deaths of head-injured patients who talked after the injury, 26 per cent had an airway obstruction, 22 per cent had hypotension (primarily intraoperative), and 17 per cent had poorly controlled seizures. 2 The anaesthetist has the technical skills and the knowledge of physiology and pharmacology to make a major ctmtribution to the well being of these patients.…”
mentioning
confidence: 99%