The otolithic organ as a receptor of vestibular hearing revealed by vestibular-evoked myogenic potentials in patients with inner ear anomalies

Sheykholeslami, Kianoush; Kaga, Kimitaka

doi:10.1016/s0378-5955(02)00278-2

Cited by 48 publications

(40 citation statements)

References 31 publications

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“…We agree with the conclusions of Sheykholeslami and Kaga [6] for which the frequency tuning of the saccule makes this terminal organ potentially sensitive to a wide range of natural sound sources, including the human voice.…”

Section: Introductionsupporting

confidence: 91%

“…The increased P1 latency in Y-PD rather than in Y-NH appears to be the only discordant data (Table 3). Although the P1 latency is generally considered the most reliable marker in the lesion of the central vestibular pathways [4][5][6][7][8][9][10][11], we interpret the increase in Y-PD as isolated data, not observing similar enhancement in A-PD. Therefore we do not believe that there are lesions of the nervous efferent pathways.…”

Section: Discussionmentioning

confidence: 58%

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Compensatory role of saccule in deaf children and adults: Novel hypotheses

et al. 2013

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Section: Introductionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 58%

Compensatory role of saccule in deaf children and adults: Novel hypotheses

et al. 2013

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“…There is considerable evidence that the p13-n23 waveform component of vestibular evoked myogenic potentials (VEMPs) in humans reflects activation of a vestibulocollic reflex originating in the saccule/inferior vestibular nerve and terminating in the motoneurons of the neck musculature (Colebatch et al, 1994;Halmagyi & Colebatch, 1995;Murofushi et al, 1996Murofushi et al, , 1998Todd et al, 2000;Ochi & Ohashi, 2001;Al-Sebeih & Zeitouni, 2002;Sheykholeslami & Kaga, 2002;Magliulo et al, 2003). As a clinical procedure, VEMP testing has provided information regarding otolith and inferior vestibular nerve function in healthy individuals as well as patients with Ménière's disease (Robertson & Ireland, 1995;deWaele et al, 1999;Shojaku et al, 2001;Young et al, 2003), vestibular neuritis (Ochi et al, 2003;Brantberg et al, 2003;Monobe & Murofushi, 2004), vestibular schwannoma (Murofushi et al, 1998;Matsuzaki et al, 1999;Tsutsumi et al, 2001), and superior semicircular canal dehiscence (Brantberg et al, 1999;Brantberg et al, 2004).…”

Section: Sumariomentioning

confidence: 99%

Properties of binaural vestibular evoked myogenic potentials elicited with air-conducted and bone-conducted tone bursts

Bhagat

2006

International Journal of Audiology

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The purpose of this investigation was to compare the effects of monaural and binaural stimulation on unilaterally-measured vestibular evoked myogenic potential (VEMP) magnitude and latency. The subjects were eighteen normal-hearing adults with no history of vestibular disease. Monaural VEMPs were acquired with air-conducted (AC) and bone-conducted (BC) 500 Hz tone bursts presented at 95 dB nHL and 70 dB nHL, respectively. These stimuli were simultaneously paired with 95 dB nHL contralateral tone bursts at 250, 500, 750, or 1000 Hz during acquisition of binaural VEMPs. Results indicated that AC-VEMP relative magnitudes decreased in each of the binaural conditions compared to the monaural condition. However, no changes in relative magnitude between conditions occurred for BC-VEMPs. Similar latencies were observed for monaural and binaural VEMPs. Differences in bilateral interaction seen between the AC-VEMP and BC-VEMP conditions are consistent with modification of sound transmission through the ear during presentations of binaural sound.

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“…In a report about vestibular side effects of extremely loud sounds, von Békésy (1935) speculated that the movement of the stapes might cause eddies that spread to the vestibular organs. In humans, the vestibular organ with the highest sound sensitivity seems to be the sacculus (Townsend and Cody, 1971;Todd et al, 2000;Sheykholeslami and Kaga, 2002), presumably due to its close proximity to the stapes. Other vestibular end organs appear to be acoustically responsive as well, though (see e.g.…”

Section: Introductionmentioning

confidence: 99%

Modeling the vestibular evoked myogenic potential

Lütkenhöner¹,

Stoll²,

Basel³

2010

Journal of Theoretical Biology

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Measuring the vestibular evoked myogenic potential (VEMP) promises to become a routine method for assessing vestibular function, although the technique is not yet standardized. To overcome the problem that the VEMP amplitude depends not only on the inhibition triggered by the acoustic stimulation of the vestibular end organs in the inner ear, but also on the tone of the muscle from which the potential is recorded, the VEMP is often normalized by dividing through a measure of the electromyogram (EMG) activity. The underlying idea is that VEMP amplitude and EMG activity are proportional. But this would imply that the muscle tone is irrelevant for a successful VEMP recording, contradicting experimental evidence. Here, an analytical model is presented that allows to resolve the contradiction. The EMG is modeled as the sum of motor unit action potentials (MUAPs). A brief inhibition can be characterized by its equivalent rectangular duration (ERD), irrespective of the actual time course of the inhibition. The VEMP resembles a polarity-inverted MUAP under such circumstances. Its amplitude is proportional to both the ERD and the MUAP rate. The EMG activity, by contrast, is proportional to the square root of the MUAP rate. Thus, the normalized VEMP still depends on the muscle tone. To avoid confounding effects of the muscle tone, the standard deviation of the EMG could be considered. But the inhibition effect on the standard deviation is small so that the measuring time would have to be much longer than usual today.

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The otolithic organ as a receptor of vestibular hearing revealed by vestibular-evoked myogenic potentials in patients with inner ear anomalies

Cited by 48 publications

References 31 publications

Compensatory role of saccule in deaf children and adults: Novel hypotheses

Compensatory role of saccule in deaf children and adults: Novel hypotheses

Properties of binaural vestibular evoked myogenic potentials elicited with air-conducted and bone-conducted tone bursts

Modeling the vestibular evoked myogenic potential

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