The origin of septin ring size control in budding yeast
Igor Kukhtevich,
Sebastian Persson,
Francesco Padovani
et al.
Abstract:The size of organelles and cellular structures needs to be tightly controlled and adjusted to the overall cell size to ensure cell function. A prominent example of a self-assembly process forming a structure whose size scales with cell size is Cdc42-driven cell polarization and subsequent septin ring formation in Saccharomyces cerevisiae. Despite extensive research, the mechanisms that determine Cdc42 cluster and septin ring size are still unclear. Combining computational modeling, live-cell imaging and geneti… Show more
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