The Origin of Patient-Derived Cancer Organoids from Pathologically Undiagnosed Specimen in Patients with Pancreatobiliary Cancers
Bomi Kim,
Jiho Park,
Hee Young Na
et al.
Abstract:Purpose
Tissue confirmation of pancreatobiliary cancer is often difficult because of the location of the tumor and structure of the surrounding blood vessels. Patient-derived cancer organoids (PDCOs) reflect the genomic characteristics of individual cancers. Although diverse attempts to construct PDCOs for various pancreatobiliary cancer models are ongoing, no research results have yet confirmed the possibility of performing a precise diagnosis on PDCOs derived from pathologically negative patient samples.
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