1993
DOI: 10.1016/0306-9877(93)90069-3
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The origin of HIV-1, the AIDS virus

Abstract: This article proposes a series of experiments to determine if cows and sheep could be used as animal models for HIV-1, the AIDS virus. To justify this effort, a substantial case is presented that HIV-1 is a natural recombinant of Bovine Leukemia Virus (BLV) and Visna Virus. This natural recombinant may have been inadvertently transferred to humans through the Intensified Smallpox Eradication Program conducted in sub-Saharan Africa in the late 1960s and most of the 1970s.

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Cited by 4 publications
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“…(KVARNFORS et al, 1975;DRISCOLL, 1978a,b;BURRIDGE, 1981;DONHAM et al, 1987;MARUYAMA et al, 1989;KANEENE, 1991a;JACOBS et al, 1992;. Foi, inclusive, sugerido que mutações no VLB teriam contribuído para o surgimento do HTLV (GALLO et al, 1983) ou que recombinações envolvendo o VLB poderiam ter dado origem ao HIV (SIEFKES, 1993).…”
Section: Introductionunclassified
“…(KVARNFORS et al, 1975;DRISCOLL, 1978a,b;BURRIDGE, 1981;DONHAM et al, 1987;MARUYAMA et al, 1989;KANEENE, 1991a;JACOBS et al, 1992;. Foi, inclusive, sugerido que mutações no VLB teriam contribuído para o surgimento do HTLV (GALLO et al, 1983) ou que recombinações envolvendo o VLB poderiam ter dado origem ao HIV (SIEFKES, 1993).…”
Section: Introductionunclassified