The oral manifestations of syphilitic disease: a case report

Streight, Kaitlyn L; Paranal, Ronald M.; Musher, Daniel M.

doi:10.1186/s13256-019-2171-z

Cited by 17 publications

(17 citation statements)

References 7 publications

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“…25,26 Secondary stage -diffuse maculopapular skin rash involving the trunk, extremities, palms, and soles. 26,27 Tertiary stage -formation of destructive granulomas (gummas). In the tongue, involvement is painless, with thickening and induration of the organ.…”

Section: Discussionmentioning

confidence: 99%

Low-Level Laser Therapy Approach of Bilateral Necrotizing Sialometaplasia of the Hard and Soft Palates

et al. 2020

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Introduction: Necrotizing sialometaplasia (NS) is a rare locally destructive inflammatory benign disease that commonly affects the minor salivary glands. It is frequently associated with the glands located in the posterior portion of the hard and soft palates. Low-level laser therapy (LLLT), also called photobiomodulation therapy (PBMT), has been deemed a substantial method for the regenerative wound process. Case Presentation: A 32-year-old male patient was referred with a chief complaint of two asymptomatic crater-like ulcers measuring approximately 1.5 cm wide on the right side of the hard and soft palates, and another measuring 0.3 cm wide on the left side of the hard palate. The lesion had two weeks of evolution followed by a previous infectious "sore throat" event that kept the patient hospitalized for 4 days. A clinical diagnosis of NS was made. LLLT was applied during 2 sessions per week, favoring the total wound healing within 2 weeks. At 3 months of clinical followup, the patient did not present any complication or relapse and was thus released. Conclusion: This is, to our knowledge, the first clinical report of LLLT applied for the management of NS. Large palatal ulcers caused by NS usually have long healing periods. The shortened healing period observed in this case encourages the inclusion of LLLT in any treatment protocol for similar lesions.

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Section: Discussionmentioning

confidence: 99%

Low-Level Laser Therapy Approach of Bilateral Necrotizing Sialometaplasia of the Hard and Soft Palates

et al. 2020

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“…The chancre resolves without treatment, and 6-8 weeks following the initial infection, secondary syphilis will present, characterized by headache, fever, and a generalized maculopapular rash affecting the palms and soles. If syphilis is left untreated, then there can be a period in which the treponemes are present but inactive, termed latent syphilis, during which patients will remain positive in serologic tests [4] . Years later, complications of tertiary syphilis may develop with a wide range of presentations due to its disseminated nature.…”

Section: Introductionmentioning

confidence: 99%

“…Radiologically, secondary and tertiary syphilis manifestations are seen frequently, but primary syphilis typically presents as an external lesion that is identified on a physical exam without a need for imaging. However, although exceedingly rare, primary syphilitic chancres also have the potential to present in atypical locations such as the tonsils, a presentation which has been reported less than 10 times in existing literature and has yet to be characterized radiographically [ 3 , 4 , 6 ]. We present a case of a patient who presented with primary syphilitic chancre of the tonsil, characterized by computed tomography (CT) imaging with intravenous contrast.…”

Section: Introductionmentioning

confidence: 99%

Novel radiographic presentation of primary syphilis of the tonsil

Camps

Pavelchek

Eldaya

et al. 2021

Radiology Case Reports

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“…Although not common, hard chancre can also be extragenital, affecting mainly anal or oral sites. The lesions disappear spontaneously within a few days leaving no scars [4][5][6][7][8][9] . The period for the lesions to appear may vary between 10 and 90 days 4,5,7 .…”

Section: Introductionmentioning

confidence: 99%

Syphilis Diagnosis through Oral Lesions of Different Clinical Aspects: Report of 3 Cases

et al. 2021

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Syphilis is a sexually transmitted infection, caused by the anaerobic spirochete Treponema pallidum. It is characterized by a variety of clinical manifestations including the oral mucosa, mimicking several diseases, thereby making diagnosis a challenge for clinicians. Therefore, the objective of this work is to report three cases of syphilis that were diagnosed based on oral lesions of different clinical aspects. In this series of cases, the lesions were found on the tongue and hard palate and presented as white plaques, ulcers or erythematous spots associated with ulcers. In the two cases, incisional biopsy was performed, and the histopathological aspects were suggestive of syphilis. Treponemic and non-treponemic tests were positive for all the patients, confirming syphilis. Therapy with benzathine-penicillin, administered intramuscularly led to complete remission of oral lesions in all the patients. The syphilis reemergence in the last years demands its inclusion in the differential diagnosis of several oral lesions. Diagnosing syphilis by oral lesions can be difficult once it can mimic other conditions. Therefore, dentists should know the clinical aspects of this infection, since many cases may exhibit only oral manifestations, to help in the diagnosis and control of the infection spread. Keywords: Syphilis. Treponemal Infections. Oral Manifestations. ResumoA sífilis é uma infecção sexualmente transmissível, causada pela espiroqueta anaeróbia Treponema pallidum. É caracterizada por uma variedade de manifestações clínicas, incluindo a mucosa oral, podendo mimetizar várias doenças, tornando o diagnóstico um desafio. Portanto, o objetivo deste trabalho é relatar três casos de sífilis diagnosticados a partir de lesões orais de diferentes aspectos clínicos. Nesta série de casos, as lesões foram encontradas na língua e palato duro e apresentadas como placas brancas, úlceras ou manchas eritematosas associadas a úlceras. Em dois casos, foi realizada biópsia incisional e os aspectos histopatológicos foram sugestivos de sífilis. Os testes treponêmicos e não treponêmicos foram positivos para todos os pacientes, confirmando a sífilis. A terapia com penicilina benzatina, administrada por via intramuscular, levou à remissão completa das lesões orais em todos os pacientes. O ressurgimento da sífilis nos últimos anos exige sua inclusão no diagnóstico diferencial de várias lesões bucais. O diagnóstico da sífilis por lesões orais pode ser difícil, pois pode mimetizar outras condições. Portanto, o dentista deve conhecer os aspectos clínicos dessa infecção, pois muitos casos podem apresentar apenas manifestações orais, para auxiliar no diagnóstico e controle da disseminação da infecção. Palavras-chave: Sífilis. Infecção Treponêmica. Manifestações Orais.

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The oral manifestations of syphilitic disease: a case report

Cited by 17 publications

References 7 publications

Low-Level Laser Therapy Approach of Bilateral Necrotizing Sialometaplasia of the Hard and Soft Palates

Low-Level Laser Therapy Approach of Bilateral Necrotizing Sialometaplasia of the Hard and Soft Palates

Novel radiographic presentation of primary syphilis of the tonsil

Syphilis Diagnosis through Oral Lesions of Different Clinical Aspects: Report of 3 Cases

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