The Oral Cavity State in Renal Transplant Recipients

Gašpar, Marija; Glavina, Ana; Grubišić, Kristina; Sabol, Ivan; Bušić, Mirela; Stipetić, Marinka Mravak

doi:10.15644/asc49/3/2

Cited by 8 publications

(7 citation statements)

References 20 publications

(45 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the present study, we observed that worsening oral health after oral transplantation, due to new cases of bleeding on probing associated with dental calculus during the posttransplant period. This data agrees with studies that stated that the worsening of oral health is related to the immunosuppressive state and the neglected oral health 9‐11,23,24 . The tacrolimus regimen, used by most of the participants in this study, has been related to an increase of periodontal inflammation, inducing angiogenesis through the production of cytokines and, in turn, contributing to inflammation and consequent worsening of the periodontal condition 25,26 .…”

Section: Discussionsupporting

confidence: 91%

“…Considering that poor oral health is commonly related to kidney transplant patients, mainly due to neglect of dental care 11,12 there are two questions to be answered: (1) what is the impact of poor oral health on short‐term renal transplantation when immunosuppression is usually heavier? 13 (2) What is the incidence of acute infection from preexisting chronic odontogenic infection immediately after transplantation when immunosuppression therapy is massive?…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Poor oral health status and short‐term outcome of kidney transplantation

Sarmento

Caliento

Maciel³

et al. 2020

Special Care in Dentistry

View full text Add to dashboard Cite

Aims This study aims to know whether poor oral health increases the risk of acute rejection and hospitalization in kidney allograft recipients. Methods and results This is a prospective cohort study. The same dentist followed participants for 2 months after renal transplant for monitoring oral health (clinical evaluation, DTMF index, and CPITN index), signs of graft rejection, infection, and hospitalization. We compiled rates and reasons for hospital readmission or extended hospital stay. The CPITN had a mean score of 0.38 ± 0.71, increasing to 0.90 ± 0.84, 60 days after transplant (P < .001). No one rejected the graft in the period of study. Patients with older age (P = .009; OR: 1.07; CI 95% 1.01–1.12) were at higher risk of hospitalization at each year of age and patients presenting pretransplant dental focus (P = .001; OR: 7.23; CI 95% 2.13–24.56) had 7.23 times more chance to be hospitalized in the first 2 months after the transplant. One participant was hospitalized due to acute foci of dental infection. Conclusion There was an association between dental focus and hospital readmission/stay. However, our methods do not provide conclusive proof of causality. Hospitalization due to acute dental infection was rare.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Poor oral health status and short‐term outcome of kidney transplantation

Sarmento

Caliento

Maciel³

et al. 2020

Special Care in Dentistry

View full text Add to dashboard Cite

show abstract

“…The most commonly described condition in the literature is GH induced by CsA, with prevalence ranging from 5% to 70%, as reported in previous studies. [ 25 , 26 ] The positive relationship between inflammation and GH is widely recognized. [ 27 , 28 ] In the present study, two-thirds of HTRs routinely received CsA as immunosuppressive therapy, and nearly 40% (24 of 53) of HTRs who took CsA developed some degree of GH.…”

Section: Discussionmentioning

confidence: 99%

Oral health status of adult heart transplant recipients in China

et al. 2018

View full text Add to dashboard Cite

Limited information on the oral health status of adult heart transplant recipients (HTRs) is known, and no available data exist in China. A prerequisite dental evaluation is usually recommended for patients’ postorgan transplantation because lifelong immunosuppression may predispose them to infection spread.The aim of this study was to investigate the oral health status of Chinese adult HTRs and determine the association between oral health status and history of heart transplantation (HT).We carried out a cross-sectional study to collect clinical, demographic, socioeconomic, and behavioral data from 81 adult patients who received heart transplantation during 2014 to 2015 in China. Clinical examinations for the presence of dental plaque, dental calculus, dental caries, and periodontal health conditions were performed in a standardized manner by one trained examiner. Sociodemographic, socioeconomic, and behavioral data were self-reported using questionnaires. The prevalence of the above conditions was compared with 63 age- and sex-matched controls. General liner regression analysis was used to assess associations between mean number of decayed, missing, and filled teeth (DMFT) and mean community periodontal index of treatment needs (CPITN) scores and history of heart transplant.Mean age of the HT group was 47.7 ± 12.2 years and men accounted for 69.1% of the sample. The overall median DMFT score in the HT group was 3 (1–5) and caries prevalence was 80.2%, which were similar to the control group (P > .05). The overall mean CPITN score of the HT group was 1.84, which was significantly higher than the control group (1.07, P = .001). Participants in the HT group had worse oral hygiene status and more teeth with probing depth ≥ 4 mm than controls (P = .043). Compared with participants who had no history of heart transplantation, HTRs presented worse periodontal health conditions (mean CPITN score, adjusted odds ratio (OR) = 1.39, 95% confidence interval (CI) = 1.12–1.71, P = .003) and similar dental caries status (DMFT score, adjusted OR = 0.58, 95% CI = 0.37–0.91, P = .058).Periodontal health status was positively associated with history of heart transplantation in Chinese adult HTRs.

show abstract

“…A study assessing the oral health of renal transplant patients found a 31% increase in the incidence of oral mucosal lesions including erythematous, keratotic lesions, and gingival hyperplasia compared to a control group. 8 Oral lesions and gingival hyperplasia are associated with and induced by immunotherapeutic medications. Oral lesions may cause oral discomfort, and pain that interferes with masticatory function, swallowing, and speech.…”

Section: Discussionmentioning

confidence: 99%

Current practices and attitudes of dental practitioners regarding the provision of dental treatment for patients with solid organ transplants

Leary¹,

Coffey²,

Burke³

et al. 2023

Clinical Transplantation

View full text Add to dashboard Cite

BackgroundSolid organ transplant provides a lifeline for people with end stage organ failure. Each year the number of individuals in receipt of a solid organ transplant is increasing. Prevention of post‐transplant sepsis and infection are critical for transplant success. The oral cavity contains more than 700 different species of bacteria and is a potential reservoir for disease causing pathogens. Prior to undergoing solid organ transplant, individuals must receive a certification of dental health from a dental practitioner. There are currently no guidelines or protocols for dental practitioners to follow when certifying a patient as dentally fit. This allows for a wide variation of the term ‘dentally fit’. This survey was conducted as part of a larger study assessing the oral health of adults with cystic fibrosis ongoing in Cork University Dental School and Hospital. The aim of the study was to ascertain current practices and attitudes of dental practitioners regarding the provision of dental treatment pre and post solid organ transplantation.MethodsAn anonymous cross sectional survey of dental practitioners in Ireland was conducted.ResultsThe data collected showed a wide variation in the provision of treatment for patient undergoing or in receipt of a solid organ transplant.ConclusionIt demonstrates a need for further research to be conducted to ascertain the full impact solid organ transplant has on oral health, so that guidelines can be developed to aid both dental and medical professionals in the treatment of this vulnerable cohort.

show abstract

The Oral Cavity State in Renal Transplant Recipients

Cited by 8 publications

References 20 publications

Poor oral health status and short‐term outcome of kidney transplantation

Poor oral health status and short‐term outcome of kidney transplantation

Oral health status of adult heart transplant recipients in China

Current practices and attitudes of dental practitioners regarding the provision of dental treatment for patients with solid organ transplants

Contact Info

Product

Resources

About