2012
DOI: 10.2174/157339812800493241
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The Oral Cavity, Biofilms and Ventilator-Associated Pneumonia

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Cited by 4 publications
(2 citation statements)
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“…Additional factors may contribute to maintain the plaques and the bacterial biofilms within them, such as the impairment of salivary flow, lower levels of immunoglobulin A, increased protease production, increased pH in the oral cavity and oropharynx (6) . However, these factors are inherent to the critical conditions of these patients and their therapeutic needs.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Additional factors may contribute to maintain the plaques and the bacterial biofilms within them, such as the impairment of salivary flow, lower levels of immunoglobulin A, increased protease production, increased pH in the oral cavity and oropharynx (6) . However, these factors are inherent to the critical conditions of these patients and their therapeutic needs.…”
Section: Discussionmentioning
confidence: 99%
“…VAP develops mainly due to aspiration of pathogens that colonize the oral cavity and oropharynx (5) . During the ICU stay, patients present lower levels of immunoglobulin A, increased protease production, denuded mucous membranes, and increased pH in the oral cavity and oropharynx (6) . These factors favor the colonization by aerobic Gram-negative bacilli and Staphylococcus aureus, pathogens that are highly prevalent in critically ill patients (7) .…”
Section: Introductionmentioning
confidence: 99%