The existing problems of production logistics system of corrugated box are pointed out. The theory of SLP (Systematic Layout Planning) within facility planning and logistics analysis is employed to optimize the facility layout, production logistics system and working procedures. After analyzes the processes and its parameters of corrugated box, logistics amount is computed, and from-to table is obtained and logistics intensity is counted. And then job units relationship, non logistics factors, and comprehensive relationship for job units etc. are studied. Finally the workshop layout of corrugated box is designed. Moreover, the optimal solution is evaluated by using weighted checklist approach. Application of the new solution shows that the working procedures of corrugated box become more reasonable, and the workshop attains the logistics smooth, so the production efficiency of corrugated box is enhanced, and its production cost is lowered.