The optimal anticoagulant therapy for mechanical heart valves in a gallbladder cancer patient with hepatic metastases

Yan, Yi–Dan; Su, Ying-Jie; Chen, Bo-Ya; Cui, Jiujie; Zhang, Zaili; Xu, Qingxiang; Z, Gu

doi:10.1097/md.0000000000012368

Cited by 2 publications

(1 citation statement)

References 17 publications

(16 reference statements)

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“…In a systematic review covering 120 clinical trials and case reports, Seshadri et al concluded that LMWH can be used as a safe anticoagulant in pregnant females with mechanical heart valves [151]. Furthermore, in a case report by Yan et al, a patient with gallbladder cancer and hepatic metastases who could not remain on warfarin therapy was successfully maintained on LMWH therapy, providing the potential for therapy other than warfarin even in non-pregnant patients [152].…”

Section: Efficacy Of Different Anticoagulant Regiments With Mechanica...mentioning

confidence: 99%

Management of Intracranial Hemorrhage in the Setting of Mechanical Heart Valve Replacement Therapy

2023

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The management of an intracranial hemorrhage in patients receiving anticoagulant therapy presents a significant challenge for medical professionals. Anticoagulant treatment is intended to prevent blood clotting, but it can worsen active brain bleeds. Despite this risk, avoiding the prothrombotic state caused by mechanical heart valves remains crucial. Guidelines on managing this issue are currently lacking, prompting a review that delves into embryonic development and anatomical functions of heart valves, valve replacement therapy for diseased valves, and the need for anticoagulants. Ultimately, recent literature and cases inform discussion regarding how best to manage intracranial hemorrhages in patients with mechanical heart valves. The expectation is that this examination will offer valuable perspectives on the handling of intracranial bleeding among individuals with mechanical heart valves and stimulate additional investigations in this intricate domain, particularly through the lens of applied mechanics.

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Section: Efficacy Of Different Anticoagulant Regiments With Mechanica...mentioning

confidence: 99%

Management of Intracranial Hemorrhage in the Setting of Mechanical Heart Valve Replacement Therapy

2023

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Gallbladder condition in patients with rheumatic fever and acquired valve defects of rheumatic origin

Strilchuk

Yatsev

2021

Modern Medical Technology

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Gallbladder (GB) and heart are linked by viscero-visceral reflexes, but little is known about the connections between GB and heart in patients with acute and chronic rheumatic heart disease. Purpose of the study. To assess the GB condition in patients with acute and chronic rheumatic disease and the difference in structural and functional sonographic parameters of heart in dependence of GB condition. Materials and methods. We examined 136 patients including 58 patients with active rheumatism (mean age 36,72 ± 3,00 years), 44 patients with chronic rheumatic heart disease (CRHD), who underwent surgical correction of the valvular defect (mean age 54,00 ± 3,69 years), and 34 patients with CHD, who were treated as inpatients withour surgery (mean age 61,48 ± 4,50 years). Results. Among 136 patients with acute and chronic forms of rheumatic heart disease, GB changes were significantly more common than intact GB (62,5 ± 4,1% vs. 37,5 ± 4,1%, p < 0,05). The incidence of GB disorders was the highest in patients with CRHD, who underwent drug treatment (76,5 ± 7,3% vs. 58,7 ± 6,5% and 50,0 ± 7,5%, both p < 0,05), which were characterized by older age. No significant differences in the incidence of various pathological conditions of GB were revealed between acute and chronic rheumatic heart disease groups. The most common pathological GB changes included signs of cholecystitis, biliary sludge and cholesterosis, cholelithiasis, the least common – GB removal due to cholelithiasis. Patients with biliary autonomic viscero-visceral cardioneuropathy differed from those with intact GB by the thickening of the interventricular septum and posterior wall of the left ventricle, which correlated with the increased duration of inpatient treatment, diastolic hypertension and lower alanine aminotransferase. Conclusions. In patients with acute and chronic forms of rheumatic heart disease, the GB condition is often changed. These changes affect heart condition, blood pressure and carbohydrate metabolism. Keywords: gallbladder, chronic rheumatic heart disease, valvular defects, rheumatic fever, echocardiography.

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The optimal anticoagulant therapy for mechanical heart valves in a gallbladder cancer patient with hepatic metastases

Cited by 2 publications

References 17 publications

Management of Intracranial Hemorrhage in the Setting of Mechanical Heart Valve Replacement Therapy

Management of Intracranial Hemorrhage in the Setting of Mechanical Heart Valve Replacement Therapy

Gallbladder condition in patients with rheumatic fever and acquired valve defects of rheumatic origin

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