The ontogeny of immunity: Development of innate immune strength in the honey bee (Apis mellifera)

Wilson-Rich, Noah; Dres, Stephanie T.; Starks, Philip T.

doi:10.1016/j.jinsphys.2008.07.016

Cited by 195 publications

(211 citation statements)

References 112 publications

Supporting

Mentioning

189

Contrasting

Unclassified

Order By: Relevance

“…This age decrease in concentration was also found by Schmid et al (2007). However, Wilson-Rich et al (2008) observed a lower haemocyte concentration in 1-dayold bees compared to foragers, perhaps because collected bees were very young and in the process of reaching the maximum haemocyte concentration. Pollen feeding did not clearly affect the PO activity.…”

Section: Discussionsupporting

confidence: 74%

Diet effects on honeybee immunocompetence

Alaux¹,

Ducloz²,

Crauser³

et al. 2010

Biol. Lett.

662

540

View full text Add to dashboard Cite

The maintenance of the immune system can be costly, and a lack of dietary protein can increase the susceptibility of organisms to disease. However, few studies have investigated the relationship between protein nutrition and immunity in insects. Here, we tested in honeybees (Apis mellifera) whether dietary protein quantity (monofloral pollen) and diet diversity (polyfloral pollen) can shape baseline immunocompetence (IC) by measuring parameters of individual immunity (haemocyte concentration, fat body content and phenoloxidase activity) and glucose oxidase (GOX) activity, which enables bees to sterilize colony and brood food, as a parameter of social immunity. Protein feeding modified both individual and social IC but increases in dietary protein quantity did not enhance IC. However, diet diversity increased IC levels. In particular, polyfloral diets induced higher GOX activity compared with monofloral diets, including protein-richer diets. These results suggest a link between protein nutrition and immunity in honeybees and underscore the critical role of resource availability on pollinator health.

show abstract

Section: Discussionsupporting

confidence: 74%

Diet effects on honeybee immunocompetence

Alaux¹,

Ducloz²,

Crauser³

et al. 2010

Biol. Lett.

662

540

View full text Add to dashboard Cite

show abstract

“…Moreover, the constant and relatively high temperature and humidity levels maintained in a bee nest provide the perfect environment for the incubation of all kinds of microorganisms, such as protozoa, fungi, bacteria and viruses. Like all animals, individual honeybees recruit physiological and immunological defence against disease agents (Evans et al, 2006;Schmid et al, 2008;Wilson-Rich et al, 2008). Moreover, as well as individual immunity, honeybees also show several physiological, behavioural and organizational colony-level adaptations such as spatial and behavioural compartmentalization of worker bees on the nest (Naug and Camazine, 2002;Naug, 2008), social fever (Starks et al, 2000), nest construction and enrichment with antimicrobial material (Simone et al, 2009;Baracchi and Turillazzi, 2010;Baracchi et al, 2011), grooming (Kolmes, 1989;Boecking and Spivak, 1999), hygienic behaviour (Rothenbuhler and Thompson, 1956;Spivak and Gilliam, 1998a,b;Richard et al, 2008), undertaking (Visscher, 1983) and self-removing (Kralj and Fuchs, 2006;Naug and Gibbs, 2009;Rueppell et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Evidence for antiseptic behaviour towards sick adult bees in honey bee colonies

Baracchi

Fadda

Turillazzi

2012

Journal of Insect Physiology

103

View full text Add to dashboard Cite

a b s t r a c tSocial life is generally associated with an increased risk of disease transmission, but at the same time it allows behavioural defence at both the individual and collective level. Bees infected with deformed-wing virus were introduced into observation hives; through behavioural observations and chemical analysis of cuticular hydrocarbons from healthy and infected bees, we offer the first evidence that honeybee colonies can detect and remove infected adult bees, probably by recognising the cuticular hydrocarbon profiles of sick individuals. We also found that health-compromised colonies were less efficient at defending themselves against infected bees, thus facing an ever increasing risk of epidemics. This work reveals a new antiseptic behaviour that can only be interpreted as an adaptation at colony level and one which should be considered an element of the social immunity system of the beehive, re-enforcing the view of a colony as an integrated organism.

show abstract

“…The nutritional status of individual bees was also analyzed consisting of two parameters: fat bodies and soluble protein content on the abdomen. The former corresponded to an organ in bees that was related with the storage of lipids and proteins required for different metabolic activities (de Oliveira & da Cruz-Landim, 2003), synthesis of different proteins like vitellogenin (Amdam & Omholt, 2002;Corona et al, 2007) and humoral immune by the synthesis of antimicrobial peptides (Brown, Moret & Schmid-hempel, 2003;Wilson-Rich, Dres & Starks, 2008). The major component of fat body is lipid representing more than 50 % of dry weight and being a measure of bee health (Arrese & Soulages, 2010).…”

Section: Discussionmentioning

confidence: 99%

“…1). Fat bodies were measured according to Wilson-Rich et al (2008). Abdomens were severed from thoraces and dried for three days at room temperature and then were weighed and washed in ethyl ether for 24 h until the fat as dissolved.…”

Section: Colony Bee: Parameters Testedmentioning

confidence: 99%

Effects of Lactobacillus Johnsonii AJ5 Metabolites on Nutrition, Nosema Ceranae Development and Performance of Apis Mellifera L.

Piano

Maggi

Pellegrini

et al. 2017

Journal of Apicultural Science

View full text Add to dashboard Cite

A b s t r a c t The European honey bee (Apis mellifera L.) is known to be affected by such stress factors as pathogen load, poor nutrition and depressed immunity. Nosema ceranae is one of the main parasites that affect colony populations. The relationship between the stress factors and honey bee-bacteria symbiosis appears as an alternative to enhance bee health. The aim of this study was to evaluate the effect of the oral administration of bacterial metabolites produced by Lactobacillus johnsonii AJ5 on nutritional parameters, the N. ceranae development and the performance of A. mellifera colonies. Laboratory assays were performed and demonstrated that the bacterial metabolites did not have a toxic effect on bees. Field trial showed an increase of colonies population over time. Also, a decreasing trend of fat bodies per bee was detected in all colonies but there were no evident changes on abdomen protein content at the end of the assay. Lastly, N. ceranae prevalence showed a tendency to reduce with the organic acids. Future studies should be performed to increase our knowledge of the physiological effects of bacterial metabolites on the health of bee colonies.

show abstract

The ontogeny of immunity: Development of innate immune strength in the honey bee (Apis mellifera)

Cited by 195 publications

References 112 publications

Diet effects on honeybee immunocompetence

Diet effects on honeybee immunocompetence

Evidence for antiseptic behaviour towards sick adult bees in honey bee colonies

Effects of Lactobacillus Johnsonii AJ5 Metabolites on Nutrition, Nosema Ceranae Development and Performance of Apis Mellifera L.

Contact Info

Product

Resources

About