“…The repair of skull defects (by means of acrylates) with open paranasal sinuses was until recently contraindicated because of the danger of infection [6,74,141]. Today this condition represents only relative contraindication since new forms of methylmethacrylates into which antibiotics are incorporated (Palacos® R with Gentamycin®, Schering; Riphocim-Palacos® R, Merck) have appeared [87,133].…”