The olfactory striae: A historical perspective on the inconsistent anatomy of the bulbar projections

Abstract

Central olfactory pathways (i.e., projection axons of the mitral and tufted cells), and especially olfactory striae, lack common terminology. This is due to their high degree of intra‐ and interindividual variability, which has been studied in detail over the past century by Beccari, Mutel, Klass, Erhart, and more recently, by Duque Parra et al. These variations led to some confusion about their number and anatomical arrangement. Recent advances in fiber tractography have enabled the precise in vivo visualization of human olfactory striae and the study of their projections. However, these studies require their algorithms to be set up according to the presumed anatomy of the analyzed fibers. A more precise definition of the olfactory striae is therefore needed, not only to allow a better analysis of the results but also to ensure the quality of the data obtained. By studying the various published works on the central olfactory pathways from the first systematic description by Soemmerring to the present, I have traced the different discussions on the olfactory tracts and summarized them here. This review adopts a systematic approach by addressing each stria individually and tracing the historical background of what was known about it in the past, compared to the current knowledge. The chronological and organized approach used provides a better understanding of the anatomy of these essential structures of the olfactory system.