The Oleate-Stimulated Phospholipase D, PLD , and Phosphatidic Acid Decrease H2O2-Induced Cell Death in Arabidopsis

Genome-wide analysis and expression profiling of the phospholipase D gene family in Gossypium arboreum

“…In Arabidopsis, the ortholog of GaPLD2, AtPLD, was proven to be activated by H 2 O 2 . Deficiency of AtPLD could render Arabidopsis cells more sensitive to H 2 O 2 -promoted programmed cell death than the wild type (Wang and Wang, 2001;Wang et al, 2006;Zhang et al, 2003;Zhang et al, 2005;Zhang et al, 2009). Furthermore, a recent study suggested that AtPLD could interact with another cytosolic glycolytic enzyme, glyceraldehyde-3-phosphate dehydrogenase, and this interaction was promoted by ROS.…”

Different Signaling and Cell Death Roles of Heterotrimeric G Protein α and β Subunits in the Arabidopsis Oxidative Stress Response to Ozone

“…The PA generated by phospholipase Da upon activation and dissociation of Ga inhibits the activity of the ABI1-and ABI2-encoded phosphatases, which negatively regulate ABA signaling through the stress-activated MAPK cascade (Zhang et al, 2004). The observations that PA both increases and decreases ROS-associated cell death may find its explanation in the balance between the signaling and cell death roles of ROS (Zhang et al, 2003;Park et al, 2004).…”

Phosphatidic Acid Binds to Cytosolic Glyceraldehyde-3-phosphate Dehydrogenase and Promotes Its Cleavage in Arabidopsis

“…The minor membrane lipid phosphatidic acid (PA) 2 has been shown as an important lipid messenger that mediates a variety of cellular and physiological processes in plants (1)(2)(3). The cellular level of PA is increased under various stress conditions, such as treatments of abscisic acid (ABA) (4), osmotic stress (5-7), oxidative stress (8), pathogen infection (9,10), and cold and freezing conditions (11)(12)(13). In addition, PA is involved in regulating normal plant growth and development, particularly in roots (14,15) and pollen tubes (16,17).…”