The present study deals with the green synthesis of titanium dioxide nanoparticles (nTiO 2 ) using Murraya koenigii leaf extract without any catalyst, template, and surfactant. Colloidal nTiO 2 were synthesized by reacting aqueous titanium(IV) isopropoxide with M. koenigii leaf extract under controlled ultrasound cavitation. This study significantly deals with (i) the concentration of titanium(IV) isopropoxide, (ii) the concentration of M. koenigii leaf extract, (iii) rate and time of reaction, (iv) intensity and pulse rate of ultrasound, which had been investigated and optimized for the controllable size and shape of nTiO 2 particles. The size and shape of nTiO 2 particle were confirmed by using transmission electron microscopy, whereas the size was calculated from XRD spectra using Scherer's formula. Moreover, the effect of nTiO 2 particle on properties of isotactic polypropylene-ethylene propylene diene monomer (iPP-EPDM) blends was studied. The physical properties (mechanical, thermal, and swelling) were found to be improved significantly with increasing amount of loading of nTiO 2 particles. This increment in properties was due to uniform dispersion of nTiO 2 particles, which can be clearly observed in FE-SEM. C 2015 Wiley Periodicals, Inc. Adv Polym Technol 201 , , 21595; View this article online at wileyonlinelibrary.com.