The Occurrence of Lymphocytes with Bilobed Nuclei in Cyclotron Personnel

Low-Energy Laser-Driven Ultrashort Pulsed Electron Beam Irradiation-Induced Immune Response in Rats

“…The formation of bilobed lymphocytes after electron beam exposure is an interesting phenomenon, which was first described by cyclotron personnel at the University of Rochester in 1948-1951 [39], and then in humans, who received different doses of radiation [34][35][36][37][38][39][40][41][42][43].…”

Effect of Small Measured Doses of Radiation on Lymphocyte Morphology in Man

“…When these observations came to our attention a program was initiated a t this laboratory to investigate the phenomenon on a quantitative basis. (6) presented additional data on the original group of cyclotron workers. The results suggested an increase in incidence of binucleated lymphocytes in individuals esposed intermittently or chronically to radiation at levels below 300 mr per week.…”

The White Cell Count in Relation to Occupational Radiation Dosage

“…"The findings are directed particuIarly to the attention of persons concerned with the prevention of radiation injuries because the increased incidence of binucleate lymphocytes appears to be related to exposure to exceptionally small amounts of radiation" (INGRAM et al, 1952). It is suggested that "examination for the presence of these cells serves as a practicable and sensitive adjunct to physical monitoring".…”