The Nubians of Kom Ombo: Serum and Red Cell Protein Types

Bertin, Terry; Harris, J.E.; Ferrell, Robert E.; Schull, William J.

doi:10.1159/000152933

Cited by 8 publications

(11 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The frequency of G6PD deficiency we report here for Egyptians, Irianians, and Lebanese are in general agreement with previous reports [13, 14, 15, 16](table 4). However, we obtained a frequency of 3.6% for Jordanians.…”

Section: Discussionsupporting

confidence: 93%

“…This frequency is, however, lower than the previously reported values of 0–2% for Egypt [13, 14], 1.7% for Jordan [17], and 3.09% for Lebanon [23]. An earlier study carried out in Kuwait in 1966 in 118 samples, using the field screening method (the methaemoglobin reduction test), reported a deficiency rate of 18.9% for the entire population [24].…”

Section: Discussionmentioning

confidence: 64%

See 1 more Smart Citation

Glucose-6-Phosphate Dehydrogenase Deficiency in Kuwait, Syria, Egypt, Iran, Jordan and Lebanon

Usanga

Ameen²

2000

Hum Hered

View full text Add to dashboard Cite

A total of 3,501 male subjects from six Arab countries living in Kuwait were investigated for quantitative and phenotypic distribution of red cell glucose-6-phosphate dehydrogenase (G6PD). The ethnic origins of those investigated were Kuwait, Egypt, Iran, Syria, Lebanon and Jordan. The distribution of G6PD deficiency among the different ethnic groups varied widely, ranging from 1.00% for Egyptians to 11.55% for Iranians. The activity of the normal enzyme was remarkably similar, with values ranging from 6.1 ± 0.8 to 6.5 ± 1.1 IU/g Hb. A low frequency of the Gd^A allele was found in two ethnic groups, Egyptians (0.019) and Iranians (0.014). Gd^A– was present at the very low frequency of 0.006 in another two ethnic groups, Kuwaitis and Jordanians.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 64%

Glucose-6-Phosphate Dehydrogenase Deficiency in Kuwait, Syria, Egypt, Iran, Jordan and Lebanon

Usanga

Ameen²

2000

Hum Hered

View full text Add to dashboard Cite

show abstract

“…The same slow variant of ceruloplasmin has been detected among the Fur and Baggara tribes of Jabal Marra area of the Sudan (Bayoumi et al, 1985). However, no variant form of the protein has been detected in a random sample from Khartoum (Saha et al, 1978); tribes of western Saudi Arabia @aha et al, 1979), or Egyptian Nubians (Bertin et al, 1978).…”

Section: Serum Proteinsmentioning

confidence: 78%

“…(Bayoumi et al, 1979;Banerjee et al, 1981, Saha and Banerjee, 1986, Hamza et al, 1976, although isolates of Shiati Arabs from eastern Saudi Arabia have a high Hbs frequency (Lehmann et al, 1963, Goedde et al, 1979. The Nubians of southern Egypt and northern Sudan also do not seem to possess HbS (Awny et al, 1965;Azim et al, 1974;Bertin et al, 1978). On the other hand, the introduction of Hbo-Arab is probably due t o Arab elements from North Africa .…”

mentioning

confidence: 99%

Some blood genetic markers of the Nuba and Hawazma tribes of Western Sudan

Bayoumi

Saha

1987

American J Phys Anthropol

View full text Add to dashboard Cite

Two hundred eighty subjects comprising 112 Nuba and 168 Hawazma of the Sudan were tested for the distribution of hemoglobins, eight red cell enzymes, and four serum proteins. The Nuba, the indigenous negroid tribe, had no HbS, HbO-Arab, or GdB(Khartoum) compared to the Hawazma tribe of Negro-Arab descent. The gene frequencies of the above polymorphic systems in the latter were as follows: HbS, 0.13; HbO-Arab, 0.01; GdB(Khartoum), 0.03. The frequency of GdA was higher in the Hawazma than in the Nuba. A high frequency of glucose 6-phosphate dehydrogenase (G6PD) deficiency and HpO was present in both the tribes. Essentially similar gene frequencies of Hp1, TfD, PGDC, pC, and PGM1 were observed in both Nuba and Hawazma. The average heterozygosity at five polymorphic loci was the same (0.23) in both the tribes. The above results agree with the social practice whereby people of mixed Hawazma and Nuba descent are considered members of the Hawazma tribe and confirm that racial admixture between the two groups can be seen as a process of gene flow from the Nuba to the Hawazma, even though the Nuba are the indigenous group, while the Hawazma are the new settlers.

show abstract

“…The variants could be identified as PHI 2-1, 3-1, and 4-1 according to Giblett (1969). No such variants of PHI were found among the Fur and other Sudanese tribes previously studied, but Bertin et al (1978) reported a single PHI variant among the Nubians of Kom Ombo in Egypt. It was not possible to establish the genetic nature of these variants because family sizes were not sufficient.…”

mentioning

confidence: 69%

A study of some genetic characteristics of the Fur and Baggara tribes of the Sudan

Bayoumi

Taha

Saha

1985

American J Phys Anthropol

View full text Add to dashboard Cite

The average inbreeding coefficients of the highly consanguineous Fur and Baggara tribes of Western Sudan were 0.04167 and 0.04450, respectively. Two hundred ninety-eight subjects from the two tribes were tested for polymorphism of hemoglobins, seven red cell enzymes, and four serum proteins. The Baggara showed a higher gene frequency of HbS and TfD and lower gene frequency of GdA and PC compared to the Fur. Both tribes showed a low gene frequency of PGM1 and high frequency of G6PD deficiency when compared to other Sudanese tribes. In spite of the high degree of inbreeding, no significant deviation from the Hardy-Weinburg equilibrium was observed in either tribe. The effects of inbreeding seem to be offset by mixing between the two tribes on Gabal Marra Plateau. The flow of the sickle gene from the Baggara into the Fur and other Sudanese tribes is discussed.

show abstract

The Nubians of Kom Ombo: Serum and Red Cell Protein Types

Cited by 8 publications

References 18 publications

Glucose-6-Phosphate Dehydrogenase Deficiency in Kuwait, Syria, Egypt, Iran, Jordan and Lebanon

Glucose-6-Phosphate Dehydrogenase Deficiency in Kuwait, Syria, Egypt, Iran, Jordan and Lebanon

Some blood genetic markers of the Nuba and Hawazma tribes of Western Sudan

A study of some genetic characteristics of the Fur and Baggara tribes of the Sudan

Contact Info

Product

Resources

About