The normal tissue sparing potential of adaptive strategies in radiotherapy of bladder cancer

An adaptive radiotherapy planning strategy for bladder cancer using deformation vector fields

“…Adaptive RT (ART) is a technique where the soft tissue information from daily imaging (in this study CBCT) is used in a systematic manner to adapt the treatment to the patient anatomy, in particular in order to account for inter-fractional anatomy changes [6][7][8][9]. For patients with urinary bladder cancer and for other pelvic treatment sites random anatomical changes are dominating [10,11] and this makes plan selection from a library of treatment plans an appealing strategy.…”

The contribution of on-line correction for rotational organ motion in image-guided radiotherapy of the bladder and prostate

“…The further comparisons of various strategies for adaptive RT (also based on the use fiducials for daily positioning according to the tumour motion) were therefore based on translations only [16]. The possibilities for correction of internal organ rotations and the related benefit have been investigated in a few previous studies.…”

State‐of‐the‐Art Report: Visual Computing in Radiation Therapy Planning

“…The work of Song et al [SSB*05] evaluates the efficacy of various image‐guided adaptive radiation therapy techniques to deliver and escalate dose to the prostate. Furthermore, the normal tissue sparing potential of adaptive strategies in radiotherapy of bladder cancer has been shown by Wright et al [WRH*08]. Open source software suites, such as DIRART [YBEN*11] or SlicerRT [PLW*12] targeting multiple aspects of IGART including registration and visualization, are freely available.…”

“…Therefore, most of the approaches in joint VC/RT research are also still under investigation. However, some approaches are already integrated into the routine—especially, those related to inter‐fraction [KZD*09, WRH*08, WLF09b].…”