The well-posedness problem of anisotropic parabolic equation with variable exponents is studied in this paper. The weak solutions and the strong solutions are introduced, respectively. By a generalized Gronwall inequality, the stability of strong solutions to this equation is established, and the uniqueness of weak solutions is proved. Compared with the related works, a new boundary value condition,
∏
i
=
1
N
a
i
x
,
t
=
0
,
x
,
t
∈
∂
Ω
×
0
,
T
, is introduced the first time and has been proved that it can take place of the Dirichlet boundary value condition in some way.