The Nonexpansile, Equilibrated Concentration of Perfluoropropane Gas in the Eye

Peters, Mark A.; Abrams, Gary W.; Hamilton, Lyle H.; Burke, Janice M.; Schrieber, Teresa M.

doi:10.1016/s0002-9394(14)73376-8

Cited by 51 publications

(31 citation statements)

References 19 publications

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“…While this method may lead to a larger variation in actual induced postoperative concentration, and theoretically lead to more postoperative IOP-related events, we did not observe this relationship. In fact, the precise resultant concentration of immediate postoperative VCFG may be impossible to determine, and commonly used “isoexpansile” concentrations are actually prone to slight expansion (18% C3F8 and 20–25% SF6) as true isovolumic gas-air fractions are actually closer to 12% and 18%, respectively [15, 16]. Considering that resultant postoperative concentrations rarely exceed 95% of air-gas exchange flush volumes, [17, 18] true isovolumic gas fractions may actually be approximated in vivo .…”

Section: Discussionmentioning

confidence: 99%

Intravitreal Fluorinated Gas Preference and Occurrence of Rare Ischemic Postoperative Complications after Pars Plana Vitrectomy: A Survey of the American Society of Retina Specialists

Sigler

Randolph

Charles

et al. 2012

Journal of Ophthalmology

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Objective. To perform a survey of the American Society of Retina Specialists (ASRS) regarding the use of vitreous cavity fluorinated gas as an adjunct to pars plana vitrectomy for retinal detachment or macular hole repair. Methods. A multiple-choice online questionnaire was administered to members of ASRS. Physician experience, gas preference for vitrectomy, and categorical estimate of observation of blinding postoperative ischemic events were recorded. Results. 282 questionnaires were completed. Mean years in vitreoretinal practice were 15 ± 10. A decrease in yearly vitrectomy volume was associated with increased number of years in practice (P = 0.011). Greater than 95% of respondents preferred fluorinated gas to air alone for both retinal detachment and macular hole repair. 38% of respondents reported at least one observation of a blinding ischemic postoperative event. Overall estimated incidence of blinding postoperative ischemic event was 0.06 events/year in practice. Conclusions. Currently, C3F8 and SF6 are the postoperative gas preference for ASRS respondents, in contrast to previous North American surveys. The occurrence of blinding ischemic events appears unrelated to number of years in practice, was reported by less than half of those surveyed, and has occurred at an infrequent rate of approximately once for every ten years of practice for those observing the phenomena.

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Section: Discussionmentioning

confidence: 99%

Intravitreal Fluorinated Gas Preference and Occurrence of Rare Ischemic Postoperative Complications after Pars Plana Vitrectomy: A Survey of the American Society of Retina Specialists

Sigler

Randolph

Charles

et al. 2012

Journal of Ophthalmology

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“…Although the most rapid increase in intraocular gas volume occurs in the first 6 hours to 8 hours, SF 6 does not reach its maximal expansion until 24 hours to 48 hours, and C 3 F 8 does not reach its maximal expansion until 72 hours to 96 hours. [15][16][17][18] Although no statistical difference was found in the rates of IOP spikes in eyes with expansile gas fills versus those with nonexpansile gas fills, the sample size may have been too small to detect statistical significance.…”

Section: Discussionmentioning

confidence: 99%

Intraocular Pressure Instability After 23-Gauge Vitrectomy

Singh¹,

Iezzi²,

Mahmoud³

2010

Retina

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“…Compared with air, intraocular gases have the advantage of providing a prolonged tamponade of retinal breaks to promote chorioretinal adhesions [30]. When injected into the vitreous cavity, the volume of SF6 doubles within 24–48h [30–32], whereas C3F8 can expand to four times its original volume within 48–72 h [30,33,34]. …”

Section: Glaucoma After Intravitreal Gas Injectionmentioning

confidence: 99%

Glaucoma management after vitreoretinal surgeries

Kornmann

Gedde

2016

Current Opinion in Ophthalmology

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Purpose of review The surgical management of retinal disorders, including scleral buckling procedures, pars plana vitrectomy, and intravitreal injections of gas or silicone oil, can lead to short-term elevations in intraocular pressure (IOP) and ultimately long-term glaucomatous damage if not treated in a timely manner. Glaucoma in these cases is commonly refractory to conventional therapies. This review highlights the treatment strategies for glaucoma in eyes that have previously undergone vitreoretinal surgery. Recent findings Although medical therapy is often used initially to control a temporary rise in IOP, laser and surgical therapy may be required to treat sustained IOP elevation and subsequent glaucomatous damage in eyes that have undergone intraocular surgery for retinal disorders. Glaucoma drainage devices are an important treatment modality, particularly when there is high risk of failure with filtering surgery. Summary Previous vitreoretinal surgery is a known risk factor for the development of glaucoma. Treatment is usually initiated with medical therapy, however, surgical intervention is frequently required to control IOP and prevent progressive glaucomatous damage in patients with refractory glaucoma.

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The Nonexpansile, Equilibrated Concentration of Perfluoropropane Gas in the Eye

Cited by 51 publications

References 19 publications

Intravitreal Fluorinated Gas Preference and Occurrence of Rare Ischemic Postoperative Complications after Pars Plana Vitrectomy: A Survey of the American Society of Retina Specialists

Intravitreal Fluorinated Gas Preference and Occurrence of Rare Ischemic Postoperative Complications after Pars Plana Vitrectomy: A Survey of the American Society of Retina Specialists

Intraocular Pressure Instability After 23-Gauge Vitrectomy

Glaucoma management after vitreoretinal surgeries

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