The Nonexistent Crystals of Macrocyclic Nickel(III). Structure of the Cobalt(III) Complex of 1,4,7-Triazacyclononane-N,N‘,N‘‘-triacetate

Abstract

Reinvestigation of the structure reported previously as the Ni(II) complex of TCNTA, by EDS analysis and crystallographic refinement, failed to confirm the presence of nickel and indicated a cobalt complex instead. It is inferred that the crystal of interest, which appeared over a period of months from a nitric acid solution of Ni(II) and the TCNTA ligand, was formed by slow crystallization of cobalt impurities to form a single crystal of the title compound.

Development of 64Cu-NOTA-Trastuzumab for HER2 Targeting: A Radiopharmaceutical with Improved Pharmacokinetics for Human Studies

“…Therefore, an optimal chelator for copper metal ion for a more stable conjugate is required for in vivo studies using 64 Cu. NOTA is an intensively investigated macrocyclic, multidentate chelator used for complexation of a broad variety of bi-and trivalent metal ions (39)(40)(41). Bifunctional NOTA forms an exceedingly stable complex with Ga 31 ions, and PET agents can feature its use.…”

A novel zinc(II) complex with the ligand 2,2′,2′′-(1,4,7-triazanonane-1,4,7-triyl)triacetate (NOTA)

“…Details on the synthesis of NOTA are given by Desreux (1980). For NOTA complexes of Al, Cr, Fe, Co, Ni, Cu, Ga and In characterized by X-ray diffraction studies, see: Boeyens & Van der Merwe (1997); Bossek et al (1995); Clarke & Martell (1991); Craig et al (1989); Jyo et al (1990); Van der Merwe et al (1983Merwe et al ( , 1985; Moore et al (1990); Wieghardt et al (1982). For general background, see: Geraldes et al (1985).…”

“…E65, m84-m85 [doi:10.1107/S1600536808041895] A novel zinc(II) complex with the ligand 2,2′,2′′-(1,4,7-triazanonane-1,4,7triyl)triacetate (NOTA) Iria Pereira-García, Alejandro Macías, Rufina Bastida and Laura Valencia S1. Comment NOTA (1,4,7-triazacyclononane-N, N′, N′′-triacetate) has a well-known preference for small metal ions, and many metal NOTA complexes (M = Al, Cr, Fe, Co, Ni, Cu, Ga and In) have been structurally characterized: (Boeyens & Van der Merwe, 1997;Bossek et al, 1995;Clarke & Martell, 1991;Craig et al, 1989;Jyo et al, 1990;Van der Merwe et al, 1983Moore et al, 1990;Wieghardt et al, 1982).…”

Chapter 20. The co-ordination chemistry of macrocyclic compounds

“…In a thorough series of kinetic experiments the acid-and chloride-catalysed complex dissociation reactions and a series of formation constants were also investigated. A 1: 1 supercomplex of the sepulchrate complex [Co'''(L)]> and calix [6]arene hexakis(sulfonic acid) (L)\ is formed in solution. The binding constant was determined in NaCl solution as 1600 dm mol\.…”