The NO/cGMP pathway in duodenal motor, mechano‐ and chemosensory responses to acid: A randomized, placebo‐controlled study with sildenafil in healthy volunteers

Abstract

Sildenafil does not affect duodenal motor, mechanosensory, and chemosensory responses to acid in healthy controls. Therefore, it is less likely that the NO pathway plays a role in the altered response to acid in functional dyspepsia patients.