The Nicotinic Acid, Biotin, and Pantothenic Acid Content of Cows' Milk

Hydroxykynureninuria: A case of Abnormal Tryptophan Metabolism Probably Due to a Deficiency of Kynureninase

“…Thus the patient would be entirely dependent on the nicotinic acid or nicotinamide, as such, present in the diet. For the first six months this consisted largely of cows' milk which yielded only 0 3-0 5 mg. of nicotinic acid per day (Lawrence, Herrington, and Maynard, 1946), whereas the recommended intake is put at 4-6 mg. per day at this age (Food and Nutrition Board, National Research Council, Washington). It is, therefore, likely that the child was suffering from an acute deficiency of nicotinic acid at this time.…”

Effects of Freeze Preservation on Nutrients

“…According to Holmes et al (1946), ice cream frozen and stored for 7 months at _23°C loses 5% of its original riboflavin, 16% of its original carotene, and 100% of its vitamin C (actually, freshly made ice cream contains little or no vitamin C). According to Lawrence et al (1946), frozen milk stored for 19 weeks at _14°C loses no biotin or nicotinic acid. …”

Pantothenic acid in ruminant nutrition: a review

“…During the first days of lactation milk PA concentrations increase and peak by about 4 mg/l between the 4th and 14th day. Afterwards concentrations decrease slightly (Lawrence et al., 1946; Pearson and Darnell, 1946; Gregory et al., 1958). With supplementations of 0.5, 2 and 16 g PA per cow per day, Marsh et al.…”

“…(1991a,b) reported that neither a prolonged release of bovine growth hormone nor an excess of energy or protein had an influence on PA concentrations in milk. Furthermore, no relationship existed between the PA content in milk and milk fat, total solids, milk‐solids‐not‐fat, caloric value, milk yield and the age of the cow (Lawrence et al., 1946). One field study on the influence of ruminally unprotected and protected supplementations of 50, 100 and 200 mg per cow per day on milk parameters exists (Bonomi, 2000).…”