The new N2, N4-diphenylpyridine-2,4-diamine deuterated derivatives as EGFR inhibitors to overcome C797S-mediated resistance

Liu, Jiadai; Nie, Wenyan; Nie, Haoran; Yao, Han; Ren, Yuanyuan; Cao, Longcai; Qiu, Jiaqi; Wang, Mengxuan; Li, Xingshu; An, Baijiao; Jia, Xian

doi:10.1016/j.bioorg.2024.107313

Bioorganic Chemistry

2024

DOI: 10.1016/j.bioorg.2024.107313

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The new N2, N4-diphenylpyridine-2,4-diamine deuterated derivatives as EGFR inhibitors to overcome C797S-mediated resistance

Jiadai Liu,

Wenyan Nie,

Haoran Nie

et al.

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Advancements in fourth-generation EGFR TKIs in EGFR-mutant NSCLC: Bridging biological insights and therapeutic development

Corvaja,

Passaro,

Attili

et al. 2024

Cancer Treatment Reviews

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Advancements in fourth-generation EGFR TKIs in EGFR-mutant NSCLC: Bridging biological insights and therapeutic development

Corvaja,

Passaro,

Attili

et al. 2024

Cancer Treatment Reviews

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The new N2, N4-diphenylpyridine-2,4-diamine deuterated derivatives as EGFR inhibitors to overcome C797S-mediated resistance

Cited by 1 publication

References 29 publications

Advancements in fourth-generation EGFR TKIs in EGFR-mutant NSCLC: Bridging biological insights and therapeutic development

Advancements in fourth-generation EGFR TKIs in EGFR-mutant NSCLC: Bridging biological insights and therapeutic development

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