“…Although lignocellulosic resources, such as energy crops and agricultural and forest residues, are readily becoming available for bioethanol production, their processing requires a costly pretreatment step to overcome their natural recalcitrance toward biological deconstruction to simple sugars (Sun and Cheng, 2002;Himmel et al, 2007;Pu et al, 2008;Somerville et al, 2010). Lignocellulosic biomass is a complex composite consisting primarily of three biopolymers (i.e., cellulose, hemicelluloses, and lignin) and its recalcitrance has been attributed to several factors such as cellulose accessibility to enzymes, lignin content/structure, lignincarbohydrate complexes, as well as the presence and structure of hemicelluloses (Wyman et al, 2005;Li et al, 2012;Leu and Zhu, 2013;Pu et al, 2013).…”