The new era in ART: INVO

INVO Procedure: Minimally Invasive IVF as an Alternative Treatment Option for Infertile Couples

“…More recently our center has pioneered the use of this procedure employing the INVOcell device within the Latin-American region [13] and has been leader in its recent introduction in countries such as Mexico, Guatemala, El Salvador, Nicaragua, Dominican Republic, Panama, Venezuela, Ecuador, Peru, Bolivia, and Brazil.…”

“…INVO procedure has been used worldwide and results from cycles performed by infertility centers around the world, in countries such as France, Germany, The Netherlands, England, USA, and Japan, have been published [ 1 , 2 , 4 – 12 ]. More recently our center has pioneered the use of this procedure employing the INVOcell device within the Latin-American region [ 13 ] and has been leader in its recent introduction in countries such as Mexico, Guatemala, El Salvador, Nicaragua, Dominican Republic, Panama, Venezuela, Ecuador, Peru, Bolivia, and Brazil.…”

IVF in Developing Economies and Low Resource Countries: An Overview

“…Intravaginal culture (IVC), also called INVO (intravaginal culture of oocytes), is an assisted reproduction procedure where oocyte fertilization and early embryo development are carried out within a gas permeable air-free plastic device, placed into the maternal vaginal cavity for incubation [18][19][20][21]. INVO can be performed in a physician's office or in a satellite facility of an IVF center.…”

“…The vaginal cavity replaces the complex in vitro fertilization (IVF) laboratory. Over 800 cycles have been published worldwide which showed a clinical pregnancy rate of 19.6 % [18][19][20][21]. The participation of the patient in the process of fertilization and early embryo development is a psychological benefit that creates a high level of acceptance of INVO.…”

Towards making assisted reproductive technology affordable and accessible: Public-private interaction

“…Other strategies aiming to make treatment more accessible, such as a simplified culture system of embryos as reported by Van Blerkom et al [5] on the first births with tWE lab, a crucial step in making IVF universally available, and the INVO cell embryo culture system, a device placed in the vagina as an incubator for culturing embryos without the need for the lab incubator, [6] still need to be evaluated in large randomised controlled clinical trials.…”