The neuropsychology of obsessive-compulsive personality disorder: a new analysis

Abstract

Nonclinical cases of OCPD showed significant cognitive inflexibility coupled with executive planning deficits, whereas decision-making remained intact. This profile of impairment overlaps with that of OCD and implies that common neuropsychological changes affect individuals with these disorders.

Predicting personality disorder functioning styles by the Chinese Adjective Descriptors of Personality: a preliminary trial in healthy people and personality disorder patients

“…It has been shown that the conscientiousness predicted workaholic characteristics [46], and workaholics scored higher on obsessive-compulsive personality disorder than healthy participants did [47]. Moreover, the obsessive-compulsive personality disorder presents a maladaptive variant of normal-range conscientiousness [48, 49].…”

The classification of Obsessive–Compulsive and Related Disorders in the ICD-11

“…Personality disorder with anankastic features is highly co-occurring with OCD and also shares a significant familial link (Bienvenu et al, 2012, Samuels et al, 2000. Furthermore, there is recent evidence for a neuropsychological profile reflecting cognitive inflexibility and perseveration in non-clinical cases of personality disorder with anankastic features that matches that of individuals with OCD (Fineberg et al, 2015).…”

Mapping Compulsivity in the DSM-5 Obsessive Compulsive and Related Disorders: Cognitive Domains, Neural Circuitry, and Treatment

“…OCD typically responds to pharmacological treatment with serotonin reuptake inhibitors (SRIs; clomipramine and selective SRIs, SSRIs) according to a dose-response relationship (higher doses needed for better clinical response) or to SSRIs combined with antipsychotic agents, and to cognitive behavior therapy (CBT) involving exposure and response prevention (ERP) ( Fineberg et al, 2015 ). Antipsychotics represent first-line treatment for Tourette’s syndrome and adjunctive antipsychotic may be preferentially effective in OCD with comorbid tics ( Bloch et al, 2006 ).…”

“…Approximately 40% of OCD patients fail to respond to standard forms of therapy ( Fineberg et al, 2015 ). Of great interest, a wide range of pharmacological compounds have been tested in treatment-resistant OCD and some have been found to be effective in small-sized trials, implicating a multiplicity of potential treatment targets and mechanisms (see Figure 2 )…”