The neuropsychiatric manifestations of Lyme borreliosis

Abstract

Lyme borreliosis (Lyme disease), a tick-borne spirochetal illness, has multisystemic involvement and is rapidly increasing in certain areas of the United States. Although its neurologic manifestations are becoming increasingly well recognized, its psychiatric presentations are not well known. The first section of this paper will provide an overview of Lyme borreliosis and a review of the relevant neuropsychiatric literature. The second section will provide clinical descriptions of some common neuropsychiatric symptoms as well as a discussion of the problems typically faced by patients with this illness. Guidelines to assist the clinician in working with these patients will be presented.

Audiologic Manifestations of Patients with Post-Treatment Lyme Disease Syndrome

“…Although a percentage of the control group had mildly reduced LDLs, none showed the dramatically reduced levels shown by the PTLDS patients. Three studies support the notion that our cohort of patients exhibited hyperacusis consistent with Lyme Disease (Fallon, et al, 1992;Goldstein & Shulman, 1996;Nields, Fallon, & Jastreboff, 1999). Goldstein and Shulman (1996) defined hyperacusis as Յ90 dB at 2 frequencies or Յ 95 dB at a single frequency.…”

“…Literature reports describe cases of psychiatric disorders, e.g., schizophrenia (Barnett, Sigmund, Roelcke, & Mundt, 1991), depression and psychosis (Kohler, 1990). Hypersensitivity to auditory, visual, tactile, gustatory (taste) and olfactory (smell) systems has been reported (Fallon, Nields, Burrascano, Liegner, DelBene, & Liebowitz, 1992).…”

“…The underlying mechanism of these symptoms is unknown and the management of these patients is controversial (Nadelman & Wormser, 1998). Reduced loudness tolerance as a manifestation of loudness discomfort level (LDL) has been reported only anecdotally (Fallon et al, 1992).…”

Relation entre lombosciatique, hernie discale et neuroborréliose : à propos de quatre observations

“…D'autres manifestations comme les polyneuropathies motrices ou sensitives isolées [6,7], les mononévrites [8], les méningites lymphocytaires [9,10] sont banales. De rares cas d'encéphalites ou d'encéphalomyélites ont été rapportés où la causalité de l'agent bactérien n'a pas toujours été démon-trée [10][11][12][13]. Les complications neurologiques apparaissent chez 10 à 40 % des patients présentant une maladie de Lyme [9,14,15].…”

Where future emerging pathogens will come from and what approaches can be used to find them, besides VFARs

“…Schizophrenia and rheumatoid arthritis are both chronic relapsing diseases of unknown etiology (Torrey & Yolken 2001). Lyme borreliosis is a tick-borne infection in humans which is associated with atypical presentations of psychiatric syndromes with relapsing and remitting progressive deterioration (Fallon et al 1993).…”