The Neurological Manifestations of Cervical Spondylosis

Brain, W. Russell; Northfield, D. W. C.; Wilkinson, Marcia

doi:10.1093/brain/75.2.187

Cited by 428 publications

(140 citation statements)

References 0 publications

Supporting

Mentioning

129

Contrasting

Unclassified

Order By: Relevance

“…Included in the differential diagnosis are: (1) cervicomedullary compression at the foramen magnum due to the Chiari 1 malformation and (2) cervical spinal cord compression due to congenital or spondylotic stenosis of the spinal canal [1,18,38]. Brain et al first described cervical spondylosis as a cause of cervical myelopathy [12]. It has since come to be recognized as the most common cause of cervical myelopathy [1,11,15,16,18,34].…”

Section: Discussionmentioning

confidence: 99%

Clinical evidence for cervical myelopathy due to Chiari malformation and spinal stenosis in a non-randomized group of patients with the diagnosis of fibromyalgia

et al. 2004

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Clinical evidence for cervical myelopathy due to Chiari malformation and spinal stenosis in a non-randomized group of patients with the diagnosis of fibromyalgia

et al. 2004

View full text Add to dashboard Cite

“…It is not a radiological diagnosis. The diagnosis of cervical myelopathy was made only in the face of symptoms and signs of disturbed function of the cervical spinal cord and/or caudal brain stem in accordance with the currently published literature [1,7,8,[11][12][13]. Neurological signs consistent with cervical myelopathy included hyper-reflexia in the upper or lower extremities, hypo-reflexia in the upper extremities in conjunction with hyper reflexia in the lower extremities, positive Hoffman sign, inversion of the periosteal reflex, positive Romberg sign, impaired tandem walk, disdiadokokinesia and dysmetria.…”

Section: Methodsmentioning

confidence: 99%

Treatment of cervical myelopathy in patients with the fibromyalgia syndrome: outcomes and implications

et al. 2007

View full text Add to dashboard Cite

Some patients with fibromyalgia also exhibit the neurological signs of cervical myelopathy. We sought to determine if treatment of cervical myelopathy in patients with fibromyalgia improves the symptoms of fibromyalgia and the patients' quality of life. A non-randomized, prospective, case control study comparing the outcome of surgical (n = 40) versus non-surgical (n = 31) treatment of cervical myelopathy in patients with fibromyalgia was conducted. Outcomes were compared using SF-36, screening test for somatization, HADS, MMPI-2 scale 1 (Hypochondriasis), and self reported severity of symptoms 1 year after treatment. There was no significant difference in initial clinical presentation or demographic characteristics between the patients treated by surgical decompression and those treated by non-surgical means. There was a striking and statistically significant improvement in all symptoms attributed to the fibromyalgia syndrome in the surgical patients but not in the non-surgical patients at 1 year following the treatment of cervical myelopathy (P £ 0.018-0.001, Chi-square or Fisher's exact test). At the 1 year follow-up, there was a statistically significant improvement in both physical and mental quality of life as measured by the SF-36 score for the surgical group as compared to the non-surgical group (Repeated Measures ANOVA P < 0.01). There was a statistically significant improvement in the scores from Scale 1 of the MMPI-2 and the screening test for somatization disorder, and the anxiety and depression scores exclusively in the surgical patients (Wilcoxon signed rank, P < 0.001). The surgical treatment of cervical myelopathy due to spinal cord or caudal brainstem compression in patients carrying the diagnosis of fibromyalgia can result in a significant improvement in a wide array of symptoms usually attributed to fibromyalgia with attendant measurable improvements in the quality of life. We recommend detailed neurological and neuroradiological evaluation of patients with fibromyalgia in order to exclude compressive cervical myelopathy, a potentially treatable condition.

show abstract

“…Cervical spondylotic amyotrophy is the clinical syndrome in cervical spondylosis characterized by severe muscular atrophy in the upper extremities, with no or insignificant sensory deficit and lower extremity symptoms [51]. In 1952, Brain et al [7] first reported cases of cervical spondylosis with muscle atrophy of the upper extremities without sensory disturbance or pyramidal signs. The dissociated motor loss syndrome in cervical spondylosis was reported by Keegan [25], and the etiology of this syndrome was thought to be selective damage by bony spurs of the motor roots.…”

Section: Introductionmentioning

confidence: 99%

Cervical spondylotic amyotrophy

Jiang

Dai

2010

Eur Spine J

View full text Add to dashboard Cite

Cervical spondylotic amyotrophy is characterized with weakness and wasting of upper limb muscles without sensory or lower limb involvement. Two different mechanisms have been proposed in the pathophysiology of cervical spondylotic amyotrophy. One is selective damage to the ventral root or the anterior horn, and the other is vascular insufficiency to the anterior horn cell. Cervical spondylotic amyotrophy is classified according to the most predominantly affected muscle groups as either proximaltype (scapular, deltoid, and biceps) or distal-type (triceps, forearm, and hand). Although cervical spondylotic amyotrophy always follows a self-limited course, it remains a great challenge for spine surgeons. Treatment of cervical spondylotic amyotrophy includes conservative and operative management. The methods of operative management for cervical spondylotic amyotrophy are still controversial. Anterior decompression and fusion or laminoplasty with or without foraminotomy is undertaken. Surgical outcomes of distal-type patients are inferior to those of proximal-type patients.

show abstract

The Neurological Manifestations of Cervical Spondylosis

Cited by 428 publications

References 0 publications

Clinical evidence for cervical myelopathy due to Chiari malformation and spinal stenosis in a non-randomized group of patients with the diagnosis of fibromyalgia

Clinical evidence for cervical myelopathy due to Chiari malformation and spinal stenosis in a non-randomized group of patients with the diagnosis of fibromyalgia

Treatment of cervical myelopathy in patients with the fibromyalgia syndrome: outcomes and implications

Cervical spondylotic amyotrophy

Contact Info

Product

Resources

About