The neurological complications of consumption coagulopathies

Weber, Marvin B.

doi:10.1212/wnl.18.2.185

Cited by 10 publications

(2 citation statements)

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“…57,58 Intracranial hemorrhage may be a devastating, yet subtle, presentation of DIC. [59][60][61][62] Spontaneous hemorrhage may occur in the absence of recognized cerebrovascular disease or trauma. 62,63 In patients with an acute subdural hematoma, the symptoms are nonlateralizing and may consist only of a head ache, drowsiness (or occasionally agitation), and subtle changes in higher brain function.…”

Section: Physical Findingsmentioning

confidence: 99%

“…Cerebrovascular thromboses may present with the stuttering, diffuse, erratic pattern of multi ple infarcts or with more characteristic signs and symptoms of hemispheral or brainstem stroke due to major vessel involvement. [59][60][61]65,78 Spinal artery thrombosis or embolization with associated isch emic necrosis and paralysis is, fortunately, rare. 67 Quadraplegia or paraplegia may also result from thrombosis of nutrient vessels to the spinal cord at any level.…”

Section: Physical Findingsmentioning

confidence: 99%

See 1 more Smart Citation

Clinical Aspects of Disseminated Intravascular Coagulation: A Clinician's Point of View

Baker¹

1989

Semin Thromb Hemost

151

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DIC is a disorder of coagulation that is demonstrated to occur in many settings. In view of the fulminant nature of the disorder once it is fully activated, the potential for considerable morbidity and mortality, and the difficulty in treating this syndrome, the necessity for a thorough understanding of the disorder is clear. A high index of suspicion is absolutely essential; however, this requires a thorough knowledge of the medical and surgical disorders in which DIC is likely to occur. The presenting manifestations of DIC, the time course of development of the fulminant syndrome, and the specific complications of the disorder may be intrinsically related to the specific clinical characteristics of the underlying disease. Clinical evaluation of the patient must be comprehensive and consider not only the laboratory and clinical manifestations of DIC but the triggering illness. Without the ability to treat the underlying primary illness, controlling or abating the DIC may be difficult or impossible. This comprehensive review of the disease entities in which DIC is likely to occur and the associated clinical manifestations will, it is hoped, guide a more precise definition of the overall clinical picture that confronts the clinician when evaluating a patient with possible DIC.

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