The Neurologic Complications of Congenital Heart Disease

Park, Sang C.; Neches, William H.

doi:10.1016/s0733-8619(18)30162-2

Cited by 30 publications

(9 citation statements)

References 76 publications

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“…The hemodynamic and angiographic studies performed in November '85 confirmed the severe pulmonary hypertension, increased vascular pulmonary resistance, and ventricular septal defect, leading to right-to-left reverse shunt, which are findings reported in Eisenmenger's syndrome 8 . Data reported in the anamnesis, physical examination, electrocardiogram, and chest X-ray are compatible with this hypothesis supported by the fact that patients with Eisenmenger's syndrome may have transient bacteremia, which may enter the cerebral circulation through the shunt without being filtered in the pulmonary circulation, leading to a cerebral abscess 10,11 . The hypothesis of Eisenmenger's syndrome can be questioned due to the presence of the small size of the ventricular septal defect (8mm in diameter), which, even though present, may not have been the cause of pulmonary hypertension.…”

Section: Discussionsupporting

confidence: 55%

Twenty-year-old woman with pulmonary hypertension, syncope, and severe headache

Cauduro¹,

Nobre²,

Edmar³

et al. 2001

Arq. Bras. Cardiol.

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A 20-year-old woman sought medical care due to headache and vomiting following syncope (9/22/95).The patient was born from an uneventful normal delivery at the end of a full-term pregnancy. Up to the age of 1 year and 6 months, the patient had fatigue when being fed. At the age of 7 years, she began to have fatigue on strenuous exertion and palpitations during tense situations. At the age of 8 years, she had 2 episodes of cyanosis and dyspnea on exertion accompanied by the sensation of imminent loss of consciousness. She also complained of arthralgia in her knees and ankles, and pain in her thoracic and lumbar spine. At the age of 9 years, the patient was referred to our hospital (11/26/84).The physical examination at that time (11/26/84) showed an eupneic and acyanotic child, with a regular and symmetric pulse. The heart rate was 72bpm and blood pressure was 120/90mmHg. The lung examination was normal. The heart examination showed an increased intensity of the second cardiac sound, which was palpable in the pulmonary area, where a systolic murmur could also be heard. The liver was palpated in the right costal margin, and no edema of the lower limbs was observed.The electrocardiogram (11/23/84) showed sinus rhythm, a heart rate of 79bpm, QRS axis of +110° forward, and right ventricular hypertrophy ( fig. 1). The chest X-ray showed enlargement of the right ventricle and bulging of the pulmonary trunk. Laboratory tests are shown in table I. The search for lupus erythematosus cells, antinuclear factor, and rheumatoid factor was negative.The echocardiogram (10/3/85) disclosed an aneurysm

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Section: Discussionsupporting

confidence: 55%

Twenty-year-old woman with pulmonary hypertension, syncope, and severe headache

Cauduro¹,

Nobre²,

Edmar³

et al. 2001

Arq. Bras. Cardiol.

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“…일반적으로 staphylococci와 streptococci는 세균성 뇌농양의 가장 흔한 미생물이며 20) , S. aureus와 Enterobacteriaceae는 두부 외상 및 수술 후 감염에서 발생한 뇌농양에서 가장 잘 동정되 는 것으로 알려져 있다 [8][9][10]16,19) . 본 연구에서도 수술 후 발생한 뇌농양의 배양 검사에서 S. aureus가 동정되었고, Gram-negative rod도 1례에서 확인되었다.…”

Section: 대상 및 방법unclassified

“…본 연구에서도 수술 후 발생한 뇌농양의 배양 검사에서 S. aureus가 동정되었고, Gram-negative rod도 1례에서 확인되었다. 이성 뇌농양의 보고에서 가 장 흔한 세균은 Proteus spp인데 22) , 본 연구에서도 P. 뇌농양의 발생 위치와 동정된 세균은 감염원과 밀접한 관 련이 있다 [8][9][10]16,19,21) . 이성 감염에 의한 대부분의 뇌농양은 측 두엽과 두정엽 또는 소뇌에서 주로 발견되는데, 본 연구에서 는 이성 뇌농양의 2례가 측두엽에서 발생하였다.…”

Section: 대상 및 방법unclassified

Clinical Analysis of 27 Cases of Brain Abscess

Lee

Kwon

Kim

et al. 2006

J Korean Neurotraumatol Soc

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Objective: This study was undertaken to evaluate the clinical presentation, sources of infection, outcome and microorganisms involved in the brain abscess in our locality.Methods: The case notes, radiological results and laboratory records of all 27 patients who were diagnosed as a brain abscess in our institution between 1990 and 2005, were reviewed retrospectively.Results: The mean age of the 27 patients was 37.7 years and the ratio of male to female was 23:4. The common presenting symptoms were headache, pyrexia, and changed mental status. The temporal lobe was the commonest site (11) and the frontal lobe (8) was followed. The primary sources of infection were found in 11 cases (41%), and those were bacterial endocarditis (4), prior surgery (3), otic infection (2) and trauma (2). Surgical intervention was performed in 18 of 27 patients. Culture of material drained from abscess isolated 4 microorganism from 4 cases of the 18 patients. The isolates were Staphylococcus aureus, Streptococcus mitis, Pseudomonas auresinosa and Proteus mirabilis. Three patients were died (11%) and the causes of death were medullary failure and septicemia (one patient was discharged hopelessly).Conclusion: There was a relatively high incidence of negative culture rate (67%) compared with other studies and the reason would might administration of antibiotics prior to surgery.

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“…Adverse neuro-developmental effects of CHD have been linked to chronic hypoxia, abnormal circulation leading to an increased risk of thrombosis, bacterial endocarditis, and brain abscess (O'Dougherty, Wright, Loewenson, & Torres, 1985;Park & Neches, 1993). In addition, a number of children with CHD have co-existing or associated congenital syndromes.…”

Section: Neurological Sequelae Of the Defectmentioning

confidence: 99%