The Neurogenetic Substructures of Human Consciousness

Grandy, John K.

doi:10.7710/1526-0569.1507

Cited by 10 publications

(3 citation statements)

References 31 publications

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“…Another interesting line of research is about the neurogenetic correlation of human consciousness and the related TFs. If the reader is interested in studying this research further, we recommend [24,[31][32][33].…”

Section: Discussionmentioning

confidence: 99%

Group Theory of Syntactical Freedom in DNA Transcription and Genome Decoding

Planat

Amaral

Fang

et al. 2022

CIMB

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Transcription factors (TFs) are proteins that recognize specific DNA fragments in order to decode the genome and ensure its optimal functioning. TFs work at the local and global scales by specifying cell type, cell growth and death, cell migration, organization and timely tasks. We investigate the structure of DNA-binding motifs with the theory of finitely generated groups. The DNA ‘word’ in the binding domain—the motif—may be seen as the generator of a finitely generated group Fdna on four letters, the bases A, T, G and C. It is shown that, most of the time, the DNA-binding motifs have subgroup structures close to free groups of rank three or less, a property that we call ‘syntactical freedom’. Such a property is associated with the aperiodicity of the motif when it is seen as a substitution sequence. Examples are provided for the major families of TFs, such as leucine zipper factors, zinc finger factors, homeo-domain factors, etc. We also discuss the exceptions to the existence of such DNA syntactical rules and their functional roles. This includes the TATA box in the promoter region of some genes, the single-nucleotide markers (SNP) and the motifs of some genes of ubiquitous roles in transcription and regulation.

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Section: Discussionmentioning

confidence: 99%

Group Theory of Syntactical Freedom in DNA Transcription and Genome Decoding

Planat

Amaral

Fang

et al. 2022

CIMB

View full text Add to dashboard Cite

show abstract

“…An interesting line of research is about the neurogenetic correlates of human consciousness and the related TFs. There are some papers in this direction [21], [27]- [29].…”

Section: Discussionmentioning

confidence: 99%

Group Theory of Syntactical Freedom in DNA Transcription and Genome Decoding

Planat¹,

Amaral²,

Fang³

et al. 2021

Preprint

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Transcription factors (TFs) are proteins that recognize specific DNA fragments in order to decode the genome and ensure its optimal functioning. TFs work at the local and global scales by specifying cell type, cell growth and death, cell migration, organization and timely tasks. We investigate the structure of DNA-binding motifs with the theory of finitely generated groups. The DNA ‘word’ in the binding domain -the motif- may be seen as the generator of a finitely generated group Fdna on four letters, the bases A, T, G and C. It is shown that, most of the time, the DNA-binding motifs have subgroup structure close to free groups of rank three or less, a property that we call ‘syntactical freedom’. Such a property is associated to the aperiodicity of the motif when it is seen as a substitution sequence. Examples are provided for the major families of TFs such as leucine zipper factors, zinc finger factors, homeo-domain factors, etc. We also discuss the exceptions to the existence of such a DNA syntactical rule and their functional role. This includes the TATA box in the promoter region of some genes, the single nucleotide markers (SNP) and the motifs of some genes of ubiquitous role in transcription and regulation.

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“…This key component will ultimately give rise to the human brain. When DNA consciousness gives rise to human consciousness this take place in three neurogenetic phases [12,13]. The concept of neurogenetic correlates of consciousness (NgCC) has been reflected upon philosophically [14] and neurologically [15].…”

Section: Dna Consciousnessmentioning

confidence: 99%

A Proposal of Consciousness as Both a Fundamental and Emergent Property of the Universe

Grandy¹

2015

Unified Field Mechanics

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The relationship that exits between interactions-complexity-consciousness (ICC) can be applied to degrees of consciousness at the smaller scales, e.g., as atoms and to degrees of consciousness at larger scales, e.g., the human brain. In this work I propose that the interactions obey the triadic dimensional vortical paradigm (TDVP) in where time, space, and consciousness are tethered from the origin point. As these interactions increase they ascend complexity at different scales and as the interaction-complexity value increases they give rise to higher degrees of consciousness. The higher degrees of consciousness can be feedback through the original process of the ICC-TDVP to give rise to even higher degrees of consciousness. This can be repeated an infinite number of occurrences in space and time. In this proposal the evolution of degrees of consciousness can be seen as a detailed self-replicating pattern which may be nearly the same at different emerging scales. Eventually, reset points or universal rewrite events occur, which is seen possibly at the level of DNA consciousness, cellular consciousness, and human consciousness. This theoretical work focuses on the development of a paradigm that interprets consciousness as both a fundamental and an emerging property.

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The Neurogenetic Substructures of Human Consciousness

Cited by 10 publications

References 31 publications

Group Theory of Syntactical Freedom in DNA Transcription and Genome Decoding

Group Theory of Syntactical Freedom in DNA Transcription and Genome Decoding

Group Theory of Syntactical Freedom in DNA Transcription and Genome Decoding

A Proposal of Consciousness as Both a Fundamental and Emergent Property of the Universe

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