The neuroendocrine timing of puberty

Ebling, Francis J. P.

doi:10.1530/rep.1.00367

Cited by 218 publications

(121 citation statements)

References 84 publications

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“…[30][31][32][33] The association between overweight and sexual maturation seems to be more complicated in boys since some studies have found a negative association and others (including our study) have found no association. 34,35 Weight management issues are an extremely delicate topic and in a study like ours one would expect that the overweight children would be more prone to dropout. However, this was not the case, as careful comparison of the previous features of the children and families that stayed in the study or dropped out show no significant differences.…”

Section: Discussionmentioning

confidence: 84%

Development of overweight in an atherosclerosis prevention trial starting in early childhood. The STRIP study

et al. 2006

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Context: Recent data indicate a marked increase in the prevalence of obesity among school-aged children. Thus, efficacious programmes that prevent overweight development in children are urgently needed. Objective: To evaluate the impact of repeatedly given, individualised dietary and lifestyle counselling on the prevalence of overweight during the first 10 years of life. Design and participants: This study was a part of the Special Turku Coronary Risk Factor Intervention Project for Children (STRIP), which is a prospective, randomised trial aimed at reducing the exposure of the intervention children to the known risk factors of atherosclerosis. At the child's age of 7 months, 1062 children were assigned to an intervention group (n ¼ 540) or to a control group (n ¼ 522). The intervention children received individualised counselling focused on healthy diet and physical activity biannually. Height and weight of the children were measured at least once a year. Main outcome measure: Prevalence of overweight and obesity among the intervention and control children by sex and age. Children were classified as overweight or obese if their weight for height was 420% or X40% above the mean weight for height of healthy Finnish children, respectively. Results: After the age of 2 years, there were continuously fewer overweight girls in the intervention group than in the control group. At the age of 10 years, 10.2% of the intervention girls and 18.8% of the control girls were overweight (P ¼ 0.0439), whereas 11.6% of the intervention boys and 12.1% of the control boys were overweight (PE1.00). Only three children in the intervention group were obese at some age point, whereas 14 control children were classified as obese at some age point. Conclusion: Individualised dietary and lifestyle counselling given twice a year since infancy decreases prevalence of overweight in school-aged girls even without any primary energy restrictions.

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Section: Discussionmentioning

confidence: 84%

Development of overweight in an atherosclerosis prevention trial starting in early childhood. The STRIP study

et al. 2006

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“…The first of these is the inhibitory effects of the CNS through γ -aminobutyric acid (GABA) [23] and neuropeptide Y [24] on the GnRH pulse generator. Possibly to a lesser extent, the development of a negative feedback mechanism involving sex steroids and inhibin on the GnRH pulse generator may also contribute to the juvenile pause in humans [25,26]. This inhibition of the GnRH pulse generator and the consequent inhibition of pituitary gonadotrophins and gonadal sex steroids appear to be maximal at 4 years of age [27].…”

Section: Childhoodmentioning

confidence: 99%

Reproductive ageing in women

Djahanbakhch

Ezzati

Zosmer

2007

The Journal of Pathology

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The traditional view in respect to female reproduction is that the number of oocytes at birth is fixed and continuously declines towards the point when no more oocytes are available after menopause. In this review we briefly discuss the embryonic development of female germ cells and ovarian follicles. The ontogeny of the hypothalamic-pituitary-gonadal axis is then discussed, with a focus on pubertal transition and normal ovulatory menstrual cycles during female adult life. Biochemical markers of menopausal transition are briefly examined. We also examine the effects of age on female fertility, the contribution of chromosomal abnormalities of the oocyte to the observed decline in female fertility with age and the possible biological basis for the occurrence of such abnormalities. Finally, we consider the effects of maternal age on obstetric complications and perinatal outcome. New data that have the potential to revolutionize our understanding of mammalian oogenesis and follicular formation, and of the female reproductive ageing process, are also briefly considered.

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“…Vannak, akik a szexuális érés hatásának tulajdonítanak nagyobb jelentőséget (Garn és mtsai 1986, Wang 2002, Demerath és mtsai 2004, de a bizonyítékok többsége arra utal, hogy a lányok serdülésének időzítésében a megemelkedett zsírtartalom a kritikus faktor (Kaplowitz és mtsai 2001, Davison és mtsai 2003, Ebling 2005.…”

Section: áBraunclassified

Szomatotípus dominancia és szexuális érés

Pápai¹,

Tróznai²,

Négele³

2017

Anthrop Közl

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Pápai J., Tróznai Zs., Négele Z.: Somatotype dominance and sexual maturation. The purposes of the study were 1) to examine indices of sexual maturation in athlete girls having predominantly endo-, meso-and ectomorph physique; 2) BevezetésA sheldoni szomatotípus az emberi alak megközelítésének különleges, egyedi módja. Alapjául a különböző csíralemezekből kifejlődő szervek dominanciájának gondolata szolgál (Sheldon és mtsai 1940). Az egyedi szomatotípust három független komponensendomorfia, mezomorfia, ektomorfia -együttesének tekinti, amelyek segítségével a testalakot egységes egészként ragadja meg. A formabecslő módszer vizuális megtekintésen alapul, a test mérete ebben a rendszerben nem játszik jelentős szerepet. A három domináns faktor egyben a szélsőséges variánsokat reprezentálja.A dominánsan endomorf szomatotípusra a lekerekítettség jellemző. Szövetei lágyak, csontjai kicsik és vékony kérgűek, a testsűrűsége alacsony. A belső szervek közül a táplálkozási rendszer tagjai az uralkodók. A tömeg a test közepére koncentrálódik. A törzs térfogata dominál a végtagoké felett, a has a mellkas felett, és a végtagok proximális szegmensei a disztálisak felett. A legszembetűnőbb külső jellemzője a zsírfelhalmozás, amely az abszorptív funkciók túlsúlyának a kifejeződése.A mezomorf szomatotípus dominanciája a nagy, vastag csontokban és az erőteljes izomzatban nyilvánul meg. Kötőszöveti túlsúly, arányaiban nagy szív-és érrendszer jellemzi. A test szögletes és erős. A törzs nagy és vastag izomzat borítja. A mellkas térfogata jelentősen nagyobb a has térfogatánál. A végtagok izmosak és változatos hosszúságúak. Szembetűnőek a vaskos izomzattal borított masszív disztális szegmensek.

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The neuroendocrine timing of puberty

Cited by 218 publications

References 84 publications

Development of overweight in an atherosclerosis prevention trial starting in early childhood. The STRIP study

Development of overweight in an atherosclerosis prevention trial starting in early childhood. The STRIP study

Reproductive ageing in women

Szomatotípus dominancia és szexuális érés

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