Oxford Handbooks Online 2015
DOI: 10.1093/oxfordhb/9780199352722.013.23
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The Neurobiology of Suicide and Implications for Treatment and Prevention

Abstract: Suicide has a biological component. It is the result not only of the necessary biological vulnerability, but also of multiple factors that must converge to elicit the behavior. These factors are discussed in this chapter and include genetic and epigenetic mechanisms, as well as psychopathologic, environmental, and stressful considerations, such as exposure to early adversity. We present a mathematical model with suicide as the outcome. The equation is based on a conventional stress-diathesis model, but it unde… Show more

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“…Suicide is a multidimensional phenomenon resulting from the interaction of biological (Arango & Underwood, 2015; van Heeringen, 2012), psychological (Karthick & Barwa, 2017), and relational (van Orden et al, 2010) factors. Every year 700,000 people die by suicide (WHO, 2021).…”
Section: Introductionmentioning
confidence: 99%
“…Suicide is a multidimensional phenomenon resulting from the interaction of biological (Arango & Underwood, 2015; van Heeringen, 2012), psychological (Karthick & Barwa, 2017), and relational (van Orden et al, 2010) factors. Every year 700,000 people die by suicide (WHO, 2021).…”
Section: Introductionmentioning
confidence: 99%