The Neonatal Heart: Developmental Differences, Response to Ischemia, and Protection during Cardiopulmonary Bypass
Alfred H. Stammers,
Edward L. Bove
Abstract:(J. Extra-Corpor. Tech. 18[4] p. 208–218 Winter 1986) Accompanying the advent of open heart surgery was the need to better understand the relationship between ischemic damage and cell viability. Corrective cardiac surgical procedures necessitate a flacid, bloodless field to provide the surgeon optimal exposure. This interruption of blood flow, however, has many deleterious effects. A non-homogeneous cascade of events is produced that, if allowed to proceed unchecked, will ultimately lead to cell death. The tim… Show more
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