The Need and Initial Practice of Parallel Imaging and Compressed Sensing in Hyperpolarized 13C MRI in vivo

Milshteyn, Eugene; Zhang, Xiaoliang

doi:10.4172/2167-7964.1000e133

Cited by 4 publications

(1 citation statement)

References 36 publications

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“…[12][13][14][15] Gd-EOB-DTPA-enhanced MRI provides more accurate information for characterizing and staging HCC that can facilitate the selection of accurate treatment strategy. 16,17 OATP1B3 is an uptake transporter located on the sinusoidal surface of the liver cell membrane and the main uptake transporter of SI in the HB phase. [18][19][20] According to past reports, the OATP1B3 expression in HCC is significantly related to the RE of the HB phase.…”

Section: Introductionmentioning

confidence: 99%

OATP1B3 Expression in Hepatocellular Carcinoma Correlates with Intralesional Gd-EOB-DTPA Uptake and Signal Intensity on Gd-EOB-DTPA-Enhanced MRI

Zhou¹,

Mo²,

Li³

2021

CMAR

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Background: To evaluate the predictive value of the OATP1B3 expression in hepatocellular carcinoma (HCC) for the gadolinium ethoxybenzyl-diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) uptake and the signal intensity (SI) in the hepatobiliary (HB) phase. Methods: In this retrospective study, we analyzed 69 liver nodules of 64 patients who underwent Gd-EOB-DTPA enhancement magnetic resonance imaging (MRI) before operation. Based on the SI in the HB phase, the patients were categorized into the hypointense HCC and iso-or hyperintense HCC groups. The OATP1B3 expression was detected by polymerase chain reaction (PCR) and immunohistochemistry. The differences between the expression of OATP1B3 and Gd-EOB-DTPA enhanced magnetic resonance imaging between the two groups of hepatocellular carcinoma were compared. The relationship between the OATP1B3 expression and the SI and relative enhancement (RE) was analyzed. Results: The examined HCC nodules were 59 hypointense HCC and 10 iso-or hyperintense. The relative expressions of OATP1B3, HB-phase signal, and the RE of the HB phase in isoor hyperintense were significantly higher than those of the hypointense HCC, while the RE of the HB phase increased with an increase in the OATP1B3 expression (P < 0.05). Conclusion: The OATP1B3 expression in HCC can predict the uptake of Gd-EOB-DTPA and the SI of the HB phase. We believe that the evaluation of OATP1B3 expression will facilitate the comprehension of imaging performance of HCC in Gd-EOB-DTPA-enhanced MRI.

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Section: Introductionmentioning

confidence: 99%

OATP1B3 Expression in Hepatocellular Carcinoma Correlates with Intralesional Gd-EOB-DTPA Uptake and Signal Intensity on Gd-EOB-DTPA-Enhanced MRI

Zhou¹,

Mo²,

Li³

2021

CMAR

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Dual-Tuned Coaxial-Transmission-Line RF Coils for Hyperpolarized ¹³C and Deuterium ²H Metabolic MRS Imaging at Ultrahigh Fields

Payne,

Zhao,

Bhosale

et al. 2024

IEEE Trans. Biomed. Eng.

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A Dedicated 36-Channel Receive Array for Fetal MRI at 3T

Chen

Xie

Luo

et al. 2018

IEEE Trans. Med. Imaging

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Due to a lack of fetal imaging coils, the standard commercial abdominal coil is often used for fetal imaging, the performance of which is limited by its insufficient coverage, element number, and Signal-to-noise ratio (SNR). In this paper, a dedicated 36-channel coil array, of which size can best fit the body sizes of pregnancy gestation from 20 to 37+ weeks, was designed for fetal imaging at 3T. SNR with full phase encoding and G-factor denoted as noise amplification for parallel imaging were quantitatively evaluated by phantom studies. Compared with a commercial abdominal coil array, the proposed 36-channel fetal array provides not only SNR improvements in full phase encoding (with 10% in the region where the whole fetal body was located, and up to 40% in the edge region where the fetal brain and heart may appear) but also an augmented parallel imaging capability and remarkable SNR improvements at high acceleration factors.

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The Need and Initial Practice of Parallel Imaging and Compressed Sensing in Hyperpolarized 13C MRI in vivo

Cited by 4 publications

References 36 publications

OATP1B3 Expression in Hepatocellular Carcinoma Correlates with Intralesional Gd-EOB-DTPA Uptake and Signal Intensity on Gd-EOB-DTPA-Enhanced MRI

OATP1B3 Expression in Hepatocellular Carcinoma Correlates with Intralesional Gd-EOB-DTPA Uptake and Signal Intensity on Gd-EOB-DTPA-Enhanced MRI

Dual-Tuned Coaxial-Transmission-Line RF Coils for Hyperpolarized ¹³C and Deuterium ²H Metabolic MRS Imaging at Ultrahigh Fields

A Dedicated 36-Channel Receive Array for Fetal MRI at 3T

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The Need and Initial Practice of Parallel Imaging and Compressed Sensing in Hyperpolarized 13C MRI in vivo

Cited by 4 publications

References 36 publications

OATP1B3 Expression in Hepatocellular Carcinoma Correlates with Intralesional Gd-EOB-DTPA Uptake and Signal Intensity on Gd-EOB-DTPA-Enhanced MRI

OATP1B3 Expression in Hepatocellular Carcinoma Correlates with Intralesional Gd-EOB-DTPA Uptake and Signal Intensity on Gd-EOB-DTPA-Enhanced MRI

Dual-Tuned Coaxial-Transmission-Line RF Coils for Hyperpolarized 13C and Deuterium 2H Metabolic MRS Imaging at Ultrahigh Fields

A Dedicated 36-Channel Receive Array for Fetal MRI at 3T

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Dual-Tuned Coaxial-Transmission-Line RF Coils for Hyperpolarized ¹³C and Deuterium ²H Metabolic MRS Imaging at Ultrahigh Fields