Abstract:The growing public interest in genetic risk scores for various health conditions may inspire preventive health action. However, these risk scores can be deceiving as they do not consider other, easily attainable risk factors, such as sex, BMI, age, smoking habits, parental disease status and physical activity. We show improved performance in identifying the 10% most at-risk individuals for type 2 diabetes (T2D) and coronary artery disease (CAD) by including these common risk factors. Incidence in the highest r… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.