The natural matrix reference material database of the International Atomic Energy Agency: Reference materials in support of dietary investigations

Arunachalam, J.; Bleise, A.; Mahwar, R. S.; Ramadevi, P.; Iyengar, G. V.

doi:10.1016/j.jfca.2005.07.002

Cited by 8 publications

(3 citation statements)

References 10 publications

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“…A certified reference material (CRM) is a material or substance whose one or more property values are sufficiently homogeneous, stable, and well established to be used for the calibration of an apparatus, the assessment of a measurement method, or for assigning values to ma-terials [1].…”

Section: Introductionmentioning

confidence: 99%

Certification and uncertainty evaluation of flavonoids certified reference materials

Quan¹,

Yao²,

Hou³

2013

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Flavonoids are the most widely used in the field of the food, medicine, and cosmetic due to their pharmacological functions and biological activities, such as anti-tumor, anti-inflammatory and antioxidation. This work described the assignment of purity values to 3 flavonoids certified reference materials (CRMs) including baicalein, 5,7-dihydoxy flavones and naringenine which were developed in this study according to the ISO Guides 34 and 35. The qualitative analysis was performed by liquid chromatography-mass spectrometry (LC-MS) and infrared spectroscopy (IR). The CRMs' purity values were assigned based on the weighted average of quantitative nuclear magnetic resonance method and mass balance approach with high resolution liquid chromatography-VWD. All the three CRMs with following value mass fractions: baicalein at a certified purity P ± U (k = 2) of 98.8% ± 0.8%; 5,7-dihydoxy flavones of 99.1% ± 0.7% and naringenine of 99.5% ± 1.0% respectively. The homogeneity of the CRMs was determined by an in-house validated liquid chromatographic method. Potential degradation during storage was also investigated and a shelf-life based on this value was established.

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Section: Introductionmentioning

confidence: 99%

Certification and uncertainty evaluation of flavonoids certified reference materials

Quan¹,

Yao²,

Hou³

2013

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“…According to the International Organization for Standardization (ISO), the key properties of RMs are that they be sufficiently homogeneous and well-established to be useful for the calibration of an apparatus, for the estimation of the parameters of a measurement method (e.g., sensitivity), or for the assignment of a particular measurement property (e.g., a Pb concentration) to a sample of material for which the measurement property is not yet known [19]. Uses for RMs also include validation of a new method, testing of an existing method for a new matrix, and estimation of the uncertainty in an analytical method [20][21][22][23]. Ideally, RMs also have long-term stability, are accompanied by matrix composition data, and exist in sufficient supply to be useful [24].…”

Section: Introductionmentioning

confidence: 99%

Development of candidate reference materials for the measurement of lead in bone

et al. 2008

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The production of modest quantities of candidate bone lead (Pb) reference materials is described, and an optimized production procedure is presented. The reference materials were developed to enable an assessment of the interlaboratory agreement of laboratories measuring Pb in bone; method validation; and for calibration of solid sampling techniques such as laser ablation ICP-MS. Long bones obtained from Pb-dosed and undosed animals were selected to produce four different pools of a candidate powdered bone reference material. The Pb concentrations of these pools reflect both environmental and occupational exposure levels in humans. The animal bones were harvested post mortem, cleaned, defatted, and broken into pieces using the brittle fracture technique at liquid nitrogen temperature. The bone pieces were then ground in a knife mill to produce fragments of 2-mm size. These were further ground in an ultra-centrifugal mill, resulting in finely powdered bone material that was homogenized and then sampled-scooped into vials. Testing for contamination and homogeneity was performed via instrumental methods of analysis.

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“…Examples are: successful integration of metrological principles into food safety (i.e. food labeling) measurements by internationally accredited laboratories, certification of natural matrix food-based materials for fat, protein, and other dietary measurements (Sharpless et al, 1997), and the IAEA database for reference materials (Arunachalam et al, 2006). F&N metrology is an emerging discipline and the public health and nutrition investigators should develop awareness for current concepts in measurement practices.…”

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confidence: 99%

Metrological concepts for enhancing the reliability of food and nutritional measurements

Iyengar

2007

Journal of Food Composition and Analysis

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The natural matrix reference material database of the International Atomic Energy Agency: Reference materials in support of dietary investigations

Cited by 8 publications

References 10 publications

Certification and uncertainty evaluation of flavonoids certified reference materials

Certification and uncertainty evaluation of flavonoids certified reference materials

Development of candidate reference materials for the measurement of lead in bone

Metrological concepts for enhancing the reliability of food and nutritional measurements

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