1983
DOI: 10.3109/00365528309181831
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The Natural History of Peptic Ulcer—Views in the 1980s

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Cited by 15 publications
(2 citation statements)
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“…There has been a growing recognition, however, that 50–90% of the patients who consult physicians for symptoms suggestive of peptic ulcer disease do not have an ulcer (Krag, 1982; Myren, 1983), and a prospective study suggests that only 3% of them will develop an ulcer within 6 years of initial assessment (Gregory, Davies, Evans, & Rhodes, 1972). It is now believed that non-ulcer dyspepsia represents a distinct clinical syndrome, separate from peptic ulcer disease and similar to the irritable bowel syndrome.…”
Section: Peptic Ulcer and Functional Dyspepsiamentioning
confidence: 99%
“…There has been a growing recognition, however, that 50–90% of the patients who consult physicians for symptoms suggestive of peptic ulcer disease do not have an ulcer (Krag, 1982; Myren, 1983), and a prospective study suggests that only 3% of them will develop an ulcer within 6 years of initial assessment (Gregory, Davies, Evans, & Rhodes, 1972). It is now believed that non-ulcer dyspepsia represents a distinct clinical syndrome, separate from peptic ulcer disease and similar to the irritable bowel syndrome.…”
Section: Peptic Ulcer and Functional Dyspepsiamentioning
confidence: 99%
“…To exclude peptic ulcer, gastric cancer and reflux esophagitis, an upper gastrointestinal endoscopy has to be performed before NUD is diagnosed. Moreover, since peptic ulcer disease shows a cyclic course [Myren, 1983], Helicobacter pylori (HP), the main cause of peptic ulcer disease [Marshall and Warren, 1984], has to be excluded either by biopsies taken during the endoscopy or by serology, at least if the endoscopy is performed in an asymptomatic phase. Furthermore, since HP is also an important factor in gastric carcinogenesis [Parsonnet et al 1991], it is wise to test the patients for this infection, particularly if an upper gastrointestinal endoscopy is not performed.…”
Section: Introductionmentioning
confidence: 99%