The Natural History of Idiopathic Subfoveal Choroidal Neovascularization

Ho, Allen C.; Yannuzzi, Lawrence A.; Pisicano, Kristin; DeRosa, Janet T.

doi:10.1016/s0161-6420(95)30968-2

Cited by 108 publications

(71 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These cases are diagnosed as ICNV. 77 The natural history of idiopathic subfoveal CNV is not necessarily associated with a profound loss of vision. Lesions of one disc area or smaller at the time of initial fluorescein angiography are more likely to be associated with a final visual acuity of 20/60 or better and less likely to be associated with a final visual acuity of 20/200 or worse.…”

Section: Idiopathic Cnvmentioning

confidence: 99%

See 1 more Smart Citation

Intravitreal bevacizumab for choroidal neovascularisation secondary to causes other than age-related macular degeneration

Gupta

Elagouz

Sivaprasad

2009

Eye

View full text Add to dashboard Cite

Choroidal neovascularisation (CNV) is characterised by new blood vessel growth under the retina that usually results in significant visual impairment when the fovea is involved. Though CNV is more commonly associated with age-related macular degeneration (AMD), it can occur secondary to a variety of other diseases. Recent successes with anti-angiogenic therapies suggest that they may outperform other therapies for all types of CNV. As non-AMD-related CNV cases are rare, randomised controlled trials are often not possible. This review compares the less prevalent reports of non-AMD CNV and pools evidence on the success and limitations of a variety of therapies.

show abstract

Section: Idiopathic Cnvmentioning

confidence: 99%

“…Lesions of one disc area or smaller at the time of initial fluorescein angiography are more likely to be associated with a final visual acuity of 20/60 or better and less likely to be associated with a final visual acuity of 20/200 or worse. 77 …”

Section: Idiopathic Cnvmentioning

confidence: 99%

Intravitreal bevacizumab for choroidal neovascularisation secondary to causes other than age-related macular degeneration

Gupta

Elagouz

Sivaprasad

2009

Eye

View full text Add to dashboard Cite

show abstract

“…There exists a distinct subset of young patients in whom choroidal neovascularisation (CNV) develops in the absence of any detectable primary ophthalmic or systemic disease which has been recognised to cause submacular neovascular membranes.1-3 When no apparent cause or association can be determined, the subretinal neovascular membrane in patients younger than 50 years of age is classified as idiopathic (ICNV). [4][5][6][7][8][9][10][11][12] Few cases of ICNV studied with combined fluorescein angiography and indocyanine green (ICG) angiography have been reportedy, 14 We report the cases of two patients with macular subretinal neovascular membranes which were diagnosed as idiopathic at fluorescein angiography and in which ICG angiography demonstrated abnormalities of the choroidal vasculature.…”

mentioning

confidence: 99%

Indocyanine green angiographic findings in idiopathic choroidal neovascularisation

Gharbiya

Pantaleoni

Grandinetti

et al. 1999

Eye

View full text Add to dashboard Cite

Purpose The authors report the cases of two patients affected with idiopathic choroidal neovascularisation studied with combined fluorescein angiography and indocyanine green (lCG) angiography. In particular the presence of choroidal abnormalities at ICG angiography which could not be detected by fluorescein angiography was studied.Methods Both patients underwent a complete systemic and ocular assessment. A subretinal neovascular membrane, located in the macular zone, is not frequent in patients under 50 years of age. There exists a distinct subset of young patients in whom choroidal neovascularisation (CNV) develops in the absence of any detectable primary ophthalmic or systemic disease which has been recognised to cause submacular neovascular membranes.1-3 When no apparent cause or association can be determined, the subretinal neovascular membrane in patients younger than 50 years of age is classified as idiopathic (ICNV).4-12Few cases of ICNV studied with combined fluorescein angiography and indocyanine green (ICG) angiography have been reportedy,14 We report the cases of two patients with macular subretinal neovascular membranes which were diagnosed as idiopathic at fluorescein angiography and in which ICG angiography demonstrated abnormalities of the choroidal vasculature. Case reports Case 1A healthy 30-year-old woman noted sudden, painless blurring of vision in her right eye. Medical, surgical and ocular history was unremarkable and she was taking no medications. There was no family history of eye disease.On examination 1 week after the onset of symptoms, visual acuity was 20/60 in the right eye and 20/20 in the left eye with a refractive error of 1.75 dioptres of myopia in both eyes. An Amsler grid test was altered in the right eye and normal in the left eye. There was no evidence of an afferent pupillary defect. Results of anterior segment examination were normal in both eyes. Results of dilated fundus examination of the right eye showed a grey submacular lesion surrounded by subretinal blood and an overlying neurosensory retinal detachment; the optic disc and retinal vessels were normal (Fig. la); the overlying vitreous was clear. The left fundus was normal, except for the presence of a pinpoint area of retinal pigment epithelium (RPE) atrophy in the macular region (Fig. Ib). At fluorescein angiography the lesion showed an early net-shaped hyperfluorescence which Eye (1999) 13, 621�28

show abstract

“…3 Idiopathic CNV has a better prognosis; but older patients and larger lesions fare worse, irrespective of the baseline acuity. 4 In our patient, HRD was probably caused by TTT-induced vasodilatation, and subsequent closure, 2 resulting in dehiscence of choroidal vessels, weakened by age, hypertension, atherosclerosis, and diabetes. The use of multiple burns might also have contributed to HRD, by excessive thermal damage at the overlapping edges.…”

Section: Case Reportmentioning

confidence: 59%

Massive haemorrhagic retinal detachment after transpupillary thermotherapy for choroidal neovascularisation

Shukla

Rao

Kim

2005

Eye

View full text Add to dashboard Cite

The Natural History of Idiopathic Subfoveal Choroidal Neovascularization

Cited by 108 publications

References 24 publications

Intravitreal bevacizumab for choroidal neovascularisation secondary to causes other than age-related macular degeneration

Intravitreal bevacizumab for choroidal neovascularisation secondary to causes other than age-related macular degeneration

Indocyanine green angiographic findings in idiopathic choroidal neovascularisation

Massive haemorrhagic retinal detachment after transpupillary thermotherapy for choroidal neovascularisation

Contact Info

Product

Resources

About