The natural history of endometrial polyps

Wong, Michael L.; Crnobrnja, Bojana; Liberale, Viola; Dharmarajah, Kuhan; Widschwendter, Martin; Jurkovic, D.

doi:10.1093/humrep/dew307

Cited by 44 publications

(28 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Immediately after ultrasound diagnosis of an endometrial polyp, according the guidelines for the treatment of endometrial polyps >10 mm, operative hysteroscopic polypectomy was undertaken excluding also any other coexisting pathology in the uterine cavity. 4,14,15 …”

Section: Methodsmentioning

confidence: 99%

Comparison of endometrial polyp recurrence in fertile women after office hysteroscopic endometrial polypectomy using two widely spread techniques

Ceci

Franchini²,

Cardinale

et al. 2020

J of Obstet and Gynaecol

View full text Add to dashboard Cite

Aim: To compare the recurrence of benign endometrial polyps after office hysteroscopic polypectomy performed with a bipolar electrode (BE) or a small diameter hysteroscopic tissue removal system (HTRs). Methods: From July 2018 to December 2019 we evaluated the charts of 114 asymptomatic fertile women who underwent office hysteroscopic polypectomy, 1 year before, for a single large benign endometrial polyp (size between 10 and 20 mm) using a 4 mm continuous flow hysteroscope with a BE or a 5 mm HTRs. Patients, divided into two groups according to surgical procedure, each performed exclusively by one expert gynecologist, were scheduled for a 12-month postoperative transvaginal sonography to evaluate the recurrence of endometrial polyps. Results: Forty-eight women of the BE group and 42 of the HTRs group were considered for the 1-year transvaginal sonography follow-up. Five polyps were identified in the BE group and three in the HTRs group (5/48 vs 3/42, P = n.s.). All polyps were removed hysteroscopically (in three out of five and in two out of three cases, respectively, in the same places of the previous polypectomy) and evaluated as 'benign' by the pathologist. Conclusion: Office hysteroscopic endometrial polypectomy with small HTRs compared to BE revealed at a 1-year follow-up no difference in terms of complete removal and recurrence of polyps. HTRs polypectomy resulted in less pain and significantly quicker time of procedure compared to BE. This data should be kept in mind for patient comfort any time hysteroscopic polypectomy is planned in an office setting.

show abstract

Section: Methodsmentioning

confidence: 99%

Comparison of endometrial polyp recurrence in fertile women after office hysteroscopic endometrial polypectomy using two widely spread techniques

Ceci

Franchini²,

Cardinale

et al. 2020

J of Obstet and Gynaecol

View full text Add to dashboard Cite

show abstract

“…It is a benign hyperplastic overgrowth of endometrial glands and stroma affecting 7.8% to 50% of women, with a prevalence of malignancy ranging from 1 to 3%, particularly in post-menopausal patients [97][98][99][100][101][102][103]. Spontaneous regression has been reported in 6.3 to 25% of cases [97,104]. Although its etiopathogenesis is still unknown, it is usually presented as a hormone-related condition [103,105,106].…”

Section: The Concept Of Impaired Inflammatory State Of the Endometriummentioning

confidence: 99%

Impaired inflammatory state of the endometrium: a multifaceted approach to endometrial inflammation. Current insights and future directions

Drizi¹,

Djokovic²,

Laganà³

et al. 2020

View full text Add to dashboard Cite

New insights into the complex and fine-regulated inflammatory mechanisms involved in the endometrium reveal multiple facets to the problem of endometrial inflammation. However, the entity termed chronic endometritis is to date restricted to infectious etiology and managed with antibiotics. Conversely, the concept of impaired inflammatory state of the endometrium (IISE) provides a more global approach to defective endometrial inflammation, considering both infectious and non-infectious etiology. A non-systematic review was done through a search on MEDLINE, EMBASE, Global Health, The Cochrane Library, Health Technology Assessment Database and Web of Science, research registers. Pertinent original and review articles, published in English or French until December 31, 2019, were selected. A compelling body of evidence demonstrates transient, repeated and persistent IISE to be a major factor of most problematic disorders in obstetrics/gynecology, such as endometrial polyps, unexplained infertility, miscarriage, placenta-related pathology and endometrial cancer. When scheduled accordingly, hysteroscopy can play a key role in the IISE assessment. Robust data suggests the pertinence of minimal-effective anti-inflammatory regimens for therapeutic IISE targeting. This review provides a comprehensive update on the multiple facets of inflammation in the endometrial physiology and pathology. Further research is needed to improve classification, diagnosis and treatment of IISE.

show abstract

“…They are a recognized cause of abnormal vaginal bleeding and have also been associated with subfertility and early pregnancy loss,. The ultrasound features of benign polyps in non‐pregnant women have been well‐documented, but there have so far been no reports of endometrial polyps identified on ultrasound examination during early pregnancy.…”

Section: Demographic Data Size Of Polyp and Pregnancy Outcome In Wommentioning

confidence: 99%

Ultrasound diagnosis of endometrial polyps in pregnancy

Memtsa

Jauniaux

Wong³

2018

Ultrasound in Obstet & Gyne

Self Cite

View full text Add to dashboard Cite

The natural history of endometrial polyps

Abstract: N/A.

Cited by 44 publications

References 19 publications

Comparison of endometrial polyp recurrence in fertile women after office hysteroscopic endometrial polypectomy using two widely spread techniques

Comparison of endometrial polyp recurrence in fertile women after office hysteroscopic endometrial polypectomy using two widely spread techniques

Impaired inflammatory state of the endometrium: a multifaceted approach to endometrial inflammation. Current insights and future directions

Ultrasound diagnosis of endometrial polyps in pregnancy

Contact Info

Product

Resources

About