The natural history of cigarette smoking from adolescence to adulthood: Demographic predictors of continuity and change.

Chassin, Laurie; Presson, Clark C.; Rose, Jennifer; Sherman, Steven J.

doi:10.1037/0278-6133.15.6.478

Cited by 367 publications

(296 citation statements)

References 15 publications

(33 reference statements)

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“…However, we also found deficiencies in nAChR upregulation in adolescence after prenatal nicotine exposure, effects that, along with earlier assessments indicated desensitization of CNS responses to nicotine. The deficient response to nicotinic stimulation in adolescents whose mothers smoked during pregnancy may then drive higher cigarette consumption (Chassin et al, 1996;Chen and Millar, 1998). We also observed greater deficits in cholinergic synaptic activity with the combination of prenatal and adolescent nicotine; accordingly, the impact of adolescent smoking on endogenous cholinergic activity may be worsened in the offspring of smokers.…”

Section: Discussionmentioning

confidence: 99%

“…Most smokers begin the habit in teen or preteen years (Nelson et al, 1995;Pierce and Gilpin, 1996), and initiation of smoking during this period is associated with greater daily consumption, a higher probability of addiction, and a lower probability of quitting (Chassin et al, 1996;Chen and Millar, 1998). Recent work with animal models of nicotine administration suggests that the greater susceptibility of adolescents has a biological basis.…”

Section: Introductionmentioning

confidence: 99%

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Prenatal Nicotine Exposure Alters the Response to Nicotine Administration in Adolescence: Effects on Cholinergic Systems During Exposure and Withdrawal

Abreu‐Villaça

Seidler

Tate

et al. 2004

Neuropsychopharmacol

103

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Maternal smoking during pregnancy increases the likelihood that the offspring will become smokers in adolescence. In the current study, we evaluated effects of prenatal and adolescent nicotine exposure in rats to assess whether there is a biological basis for this relationship. Pregnant rats were given nicotine or vehicle throughout pregnancy and the offspring then again received nicotine or vehicle during adolescence (postnatal days PN30-47.5), using a regimen (6 mg/kg/day by subcutaneous infusion) that produces plasma nicotine levels similar to those in smokers. Evaluations were made in the cerebral cortex and midbrain during adolescent nicotine administration (PN45) and for up to 1 month after the end of treatment. We assessed the magnitude and persistence of nicotinic acetylcholine receptor (nAChR) upregulation; in addition, we evaluated cholinergic synaptic activity by comparing the effects on choline acetyltransferase (ChAT), a constitutive marker for cholinergic nerve terminals, with those on hemicholinium-3 (HC-3) binding to the presynaptic choline transporter, which is regulated by nerve impulse activity. Prenatal nicotine exposure had only minor effects on nAChRs but produced persistent cholinergic hypoactivity (reduced HC-3 binding relative to ChAT) throughout adolescence and into adulthood (PN75). Adolescent nicotine exposure evoked robust nAChR upregulation and also suppressed cholinergic activity. Prenatal nicotine exposure reduced the upregulation of nAChRs evoked by adolescent nicotine but worsened the cholinergic hypoactivity during withdrawal. Our results indicate that prenatal nicotine exposure alters the subsequent response to nicotine in adolescence, effects that may contribute to the association between maternal smoking during pregnancy and subsequent adolescent smoking in the offspring.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Prenatal Nicotine Exposure Alters the Response to Nicotine Administration in Adolescence: Effects on Cholinergic Systems During Exposure and Withdrawal

Abreu‐Villaça

Seidler

Tate

et al. 2004

Neuropsychopharmacol

103

View full text Add to dashboard Cite

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“…Desenho e amostra do estudo Trata-se de estudo observacional seccional sobre a população de adolescentes e adultos jovens (15)(16)(17)(18)(19)(20)(21)(22)(23)(24) 13 .…”

Section: Métodosunclassified

Tabagismo entre adolescentes e adultos jovens de Belo Horizonte, Minas Gerais, Brasil: influência do entorno familiar e grupo social

2011

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The study aimed to estimate smoking prevalence in Belo Horizonte, Minas Gerais State, Brazil, and related risk factors among adolescents. We used data from the household survey conducted by the Brazilian National Cancer Institute (2002)(2003) IntroduçãoOs males do tabagismo são amplamente conhecidos e divulgados. Sabe-se que o hábito de fumar é uma das causas de aproximadamente cinquenta diferentes tipos de enfermidades, destacando-se as doenças cardiovasculares, o câncer e as doenças respiratórias obstrutivas crônicas 1 .Estudos demonstram que o início do hábito de fumar, considerado uma dependência quími-ca, é cada vez mais precoce, resultando em um aumento da prevalência de tabagismo entre adolescentes e jovens 2 . Mais de um bilhão de pessoas com 15 anos ou mais fumam diariamente e aproximadamente 80% destas vivem em países de baixa ou média renda 1 . Os adolescentes constituem uma parcela da população que tem elevado risco de consolidação do hábito de fumar, pois é exposta mais precocemente ao tabaco 2 .Na tentativa de propor intervenções para o combate ao tabagismo, com foco no grupo mais jovem que está começando a ser exposto a esse hábito, vários pesquisadores têm buscado conhecer a prevalência do problema. Na caracterização do perfil dos jovens fumantes, esses autores avaliam, na maioria das vezes, fatores individuais 2,3,4,5,6,7 . São escassos os trabalhos que abordam a interação entre fatores ambientais e individuais na determinação dos comportamentos de risco para o hábito de fumar.Tomando como base o modelo teórico proposto por Engels et al. 8 , o tabagismo entre ado-ARTIGO ARTICLE

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“…Chassin et al 1996;Bachman et al 1997), alcohol and tobacco use onset by age 12 or 13 escalated through the adolescent years, and reached an asymptote by mid young adulthood. As expected, men had higher mean levels and greater increases in drinking, yet women's smoking appeared very similar to men's, a finding that has only recently been supported in the literature (Johnston et al 1998;Duncan & Duncan 1994).…”

Section: General Trends In Drinking and Smokingmentioning

confidence: 99%

Adolescent alcohol and tobacco use: onset, persistence and trajectories of use across two samples

et al. 2002

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Aims-We examined the alcohol-tobacco relationship using two prospective, ethnically diverse samples. Trajectories of alcohol and tobacco use are portrayed overall and by sex and ethnicity. Using prospective analyses, we examine directional influences between alcohol and tobacco use, and we characterize initiation versus persistence of drinking and smoking as a function of use of the other substance.Design, setting-Data were from the National Longitudinal Study of Adolescent Health (AddHealth) and the Adolescent Health Risk Study (AHRS). Follow-up intervals for AddHealth and AHRS were 1 and 5 years, respectively.Participants-AddHealth respondents (n = 4831) were on average 14.8 years old (48% male, 23% black, 61% white) and AHRS respondents (n = 1814) were on average 16.7 years old (47% male, 44% black, 49% white).Measurements-Two alcohol consumption variables and two smoking variables were used: drinking frequency and heavy drinking frequency, and regular (current) smoking and daily number of cigarettes.Findings-Alcohol and tobacco use exhibited monotonic increases over adolescence and young adulthood. Men and white respondents reported more use than women and black respondents. Alcohol and tobacco were moderately associated at both times. Analyses revealed that prior alcohol use predicted tobacco use more strongly than the converse. Initiation of smoking was a function of prior drinking; to a lesser extent, initiation of drinking was a function of prior smoking. Persistence of smoking was a function of prior drinking and persistence of drinking was a function of prior smoking.Conclusions-Provisional support exists for the claim that alcohol use predicts tobacco use more strongly than the converse. For both drinking and smoking, onset and persistence are predicted by prior use of the other substance, and these associations were robust across sex and ethnicity.

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The natural history of cigarette smoking from adolescence to adulthood: Demographic predictors of continuity and change.

Cited by 367 publications

References 15 publications

Prenatal Nicotine Exposure Alters the Response to Nicotine Administration in Adolescence: Effects on Cholinergic Systems During Exposure and Withdrawal

Prenatal Nicotine Exposure Alters the Response to Nicotine Administration in Adolescence: Effects on Cholinergic Systems During Exposure and Withdrawal

Tabagismo entre adolescentes e adultos jovens de Belo Horizonte, Minas Gerais, Brasil: influência do entorno familiar e grupo social

Adolescent alcohol and tobacco use: onset, persistence and trajectories of use across two samples

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