2016
DOI: 10.3310/hta20220
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The natural history of Chlamydia trachomatis infection in women: a multi-parameter evidence synthesis

Abstract: The Medical Research Council grant G0801947.

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Cited by 379 publications
(171 citation statements)
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References 236 publications
(724 reference statements)
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“…Untreated CT infections can lead to severe complications (Rahm, Gnarpe and Odlind 1988;Morre et al 2000), such as pelvic inflammatory disease (PID), ectopic pregnancy and tubal factor infertility (TFI) (Bjartling, Osser and Persson 2007;Price et al 2016). It has been estimated that 6.7% of a 35-year-old women who at least once tested positive for CT will develop TFI (Low et al 2006).…”
Section: Introductionmentioning
confidence: 99%
“…Untreated CT infections can lead to severe complications (Rahm, Gnarpe and Odlind 1988;Morre et al 2000), such as pelvic inflammatory disease (PID), ectopic pregnancy and tubal factor infertility (TFI) (Bjartling, Osser and Persson 2007;Price et al 2016). It has been estimated that 6.7% of a 35-year-old women who at least once tested positive for CT will develop TFI (Low et al 2006).…”
Section: Introductionmentioning
confidence: 99%
“…Genital infection Chlamydia trachomatis is a common condition, affecting mainly young subjects, between 15 and 25 years old. It is mostly asymptomatic and can be screened in populations at risk [1]. Chlamydia trachomatis is a common pathogen of pelvic inflammatory disease (PID), and is isolated in the upper genital tract of about one-quarter of the PID patients.…”
Section: Discussionmentioning
confidence: 99%
“…Where as presence of C. trachomatis IgG was strongly associated with EP [adjusted odds ratio (OR) 5·41, 95% confidence interval (CI) 2·58-11·32], its DNA remained undetected in all tubal lesions [20]. Actually, risk factors for STIs with Chlamydia trachomatis are well identified such as age less than 25 years, occasional sexual partner, more than 2 partners in the year, same-sex partners, absence of diploma, sexual intercourse with one age and history of STI [1]. In our study, more than half of the patients had at least one risk factor.…”
Section: Discussionmentioning
confidence: 99%
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“…As a consequence, the Public Health System in England published in March 2016 a Report of the National Chlamydia Screening Program (21). This report has generated a set of estimates about the epidemiology of chlamydia infections, from its incidence, prevalence and duration of infection, and its role in the pathogenesis of PID and tubal factor infertility (TFI).…”
Section: Nucleic Acid Amplification Testmentioning
confidence: 99%