The Natural History of a Hepatic Angiosarcoma that was Difficult to Differentiate from Cavernous Hemangioma

Abstract

A 69-year old man came to our hospital complaining of abdominal pain. Contrast-enhanced computed tomography (CT) showed a 65-mm ruptured mass in Couinaud segment 5 of the liver. The mass was treated with emergent transcatheter arterial embolization (TAE), followed by partial hepatectomy. Microscopically, the mass was determined to be an angiosarcoma. Six months previously, enhanced CT had shown a 15-mm mass diagnosed as a cavernous hemangioma in the same region of the liver. Even when the enhancement pattern of a small hepatic mass resembles that of hemangioma, the mass should be reassessed within several months to exclude a diagnosis of hepatic angiosarcoma.

Surgical Treatment and Chemotherapy of Adult Primary Liver Sarcoma: Experiences from a Single Hospital in China

“…It accounts for less than 1% of primary hepatic malignancies [3, 4, 12, 13]. PLSs have several pathological types, including hemangiosarcoma, liposarcoma, leiomyosarcoma, epithelioid hemangioendothelioma, fribrosarcoma, hepatoblastoma, carcinosarcoma, malignant fibrous histiocytoma, rhabdomyosarcoma, chondrosarcoma, and undifferentiated sarcoma [4-7].…”

Primary hepatic angiosarcoma: multi-institutional comprehensive cancer centre review of multiphasic CT and MR imaging in 35 patients

“…The cross-sectional imaging features of primary hepatic angiosarcoma are largely anecdotal, since the literature is restricted to either case reports or small case series [1,2,[5][6][7][8][9][10][11][12][13]. The only imaging series to date with more than 10 patients was reported by Koyama et al in 2002 [2], who described cross-sectional imaging features in 13 patients, including three cases with multiphasic CT or MR.…”

Metastatic Angiosarcoma of Liver: A Case Report

“…(17) Follow-up imaging studies should be performed, and a diagnosis of angiosarcoma should be suspected if there is rapid enlargement. (15,18) Pathological diagnosis is very necessary. Epithelioid haemangioendothelioma (HEH), a rare, usually low-grade malignant tumor, should be considered for differential diagnosis of HA.…”