The natural course of untreated sick sinus syndrome and identification of the variables predictive of unfavorable outcome

Menozzi, Carlo; Brignole, Michele; Alboni, Paoló; Boni, Luca; Paparella, Nelly; Gaggioli, Germano; Lolli, Gino

doi:10.1016/s0002-9149(98)00605-5

Cited by 102 publications

(39 citation statements)

References 12 publications

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“…The majority of patients who have experienced syncope because of a sinus pause or marked sinus bradycardia will have recurrent syncope. 30 Not uncommonly, the natural history of SND is interrupted by other necessary medical therapies that aggravate the underlying tendency to bradycardia. 24 MOST (Mode Selection Trial) included symptomatic pauses greater than or equal to 3 seconds or sinus bradycardia with rates greater than 50 bpm, which restricted the use of indicated long-term medical therapy.…”

Section: Sinus Node Dysfunctionmentioning

confidence: 99%

“…Supraventricular tachycardia (SVT) including AF was present in 47% and 53% of patients, respectively, enrolled in a large randomized clinical trial of pacing mode selection in SND. 22,31 The incidence of sudden death is extremely low, and SND does not appear to affect survival whether untreated 30 or treated with pacemaker therapy. 32,33 The only effective treatment for symptomatic bradycardia is permanent cardiac pacing.…”

Section: Sinus Node Dysfunctionmentioning

confidence: 99%

See 1 more Smart Citation

ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities

Epstein¹,

DiMarco²,

Ellenbogen³

et al. 2008

Circulation

1,243

488

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Section: Sinus Node Dysfunctionmentioning

confidence: 99%

Section: Sinus Node Dysfunctionmentioning

confidence: 99%

ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities

Epstein¹,

DiMarco²,

Ellenbogen³

et al. 2008

Circulation

1,243

488

View full text Add to dashboard Cite

“…Untreated, sinus node dysfunction does not influence survival, 260 and asymptomatic sinus bradycardia is not an indication for pacing. 229 Thus, asymptomatic sinus bradycardia does not require inhospital monitoring.…”

Section: Sinus Bradycardiasmentioning

confidence: 99%

Update to Practice Standards for Electrocardiographic Monitoring in Hospital Settings: A Scientific Statement From the American Heart Association

Sandau¹,

Funk²,

Auerbach³

et al. 2017

Circulation

198

214

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Background and Purpose: This scientific statement provides an interprofessional, comprehensive review of evidence and recommendations for indications, duration, and implementation of continuous electro cardiographic monitoring of hospitalized patients. Since the original practice standards were published in 2004, new issues have emerged that need to be addressed: overuse of arrhythmia monitoring among a variety of patient populations, appropriate use of ischemia and QT-interval monitoring among select populations, alarm management, and documentation in electronic health records. Methods: Authors were commissioned by the American Heart Association and included experts from general cardiology, electrophysiology (adult and pediatric), and interventional cardiology, as well as a hospitalist and experts in alarm management. Strict adherence to the American Heart Association conflict of interest policy was maintained throughout the consensus process. Authors were assigned topics relevant to their areas of expertise, reviewed the literature with an emphasis on publications since the prior practice standards, and drafted recommendations on indications and duration for electrocardiographic monitoring in accordance with the American Heart Association Level of Evidence grading algorithm that was in place at the time of commissioning. Results: The comprehensive document is grouped into 5 sections: (1) Overview of Arrhythmia, Ischemia, and QTc Monitoring; (2) Recommendations for Indication and Duration of Electrocardiographic Monitoring presented by patient population; (3) Organizational Aspects: Alarm Management, Education of Staff, and Documentation; (4) Implementation of Practice Standards; and (5) Call for Research. Conclusions: Many of the recommendations are based on limited data, so authors conclude with specific questions for further research.

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“…One observational study, however, showed a relationship between the presence of prolonged recovery time at electrophysiological study and the effect of pacing on symptoms [167] . Recently Menozzi et al [168] addressed a related issue in a small prospective study, showing that the patients with a CSNRT of d800 ms had an 8 times higher risk of syncope than patients with a CSNRT below this value. The panel discussed the criteria for SNRT as a diagnostic tool for syncope but could not arrive at a consensus because of the lack of other prospective data evaluating the diagnostic value of this test.…”

Section: Task Force Report 1273mentioning

confidence: 99%

Guidelines on management (diagnosis and treatment) of syncope

Brignole¹,

Alboni²,

Benditt

et al. 2001

European Heart Journal

677

432

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The natural course of untreated sick sinus syndrome and identification of the variables predictive of unfavorable outcome

Cited by 102 publications

References 12 publications

ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities

ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities

Update to Practice Standards for Electrocardiographic Monitoring in Hospital Settings: A Scientific Statement From the American Heart Association

Guidelines on management (diagnosis and treatment) of syncope

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